V116517

DB16060InvestigationalSmall molecule

V116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)).

Mechanism: Pharmacologically active on Transient receptor potential cation channel subfamily V member 1
Curator reviewed
Formula / weight: C₁₉H₁₈ClF₃N₄O₃ · 442.82 g/mol (avg)
Code names: V-116517

Resolves to

Compound

UNIITBJ73RQT8FCAS1073616-61-1ChEMBLCHEMBL4112578

Structure

InChIKeyBMWVHVOIXZOJTJ-OAHLLOKOSA-NSMILESOC[C@@H](O)C1=CN=C(C(Cl)=C1)C1=CCN(CC1)C(=O)NC1=CC=C(C=N1)C(F)(F)F

Targets

Q8NER1TRPV1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with V116517, and which of those have an active Phase 3 trial?

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