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Displaying results 7671 - 7680 of 9886 in total
  1. Drug

    Luxdegalutamide

    go.drugbank.com/drugs/DB22370
    Investigational

    JSB462 is under investigation in clinical trial NCT07047118 (A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer

  2. Drug

    Izalontamab brengitecan

    go.drugbank.com/drugs/DB22567
    Investigational

    Izalontamab brengitecan is under investigation in clinical trial NCT07054567 (A Study of BL-B01D1 + Pembrolizumab ± Bevacizumab in Patients With Recurrent or Metastatic Cervical Cancer and Endometrial

  3. Drug

    PF-08046052

    go.drugbank.com/drugs/DB22647
    Investigational

    PF-08046052 is under investigation in clinical trial NCT05983133 (A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors).

  4. Drug

    Dengue virus serotype 4

    go.drugbank.com/drugs/DB22667
    Approved

    Dengue virus serotype 4 is a serotype of _Orthoflavivirus denguei_ known to cause dengue fever. … [A274008] It is one of four serotypes covered by Qdenga, a live, attenuated, tetravalent vaccine used for the prevention of dengue disease.

  5. Drug

    Plasmin (Human)

    go.drugbank.com/drugs/DB22676
    Investigational

    The enzyme plasmin causes clot lysis by cleaving fibrin, a clot component.[L53453]

  6. Drug

    Vusolimogene oderparepvec

    go.drugbank.com/drugs/DB23008
    ApprovedInvestigational

    Vusolimogene oderparepvec-wtpg is a genetically modified herpes simplex virus type 1 (HSV-1) oncolytic viral therapy used, in combination with [nivolumab], to treat advanced melanoma. … [L64061] The virus is engineered to express a fusogenic glycoprotein derived from gibbon ape leukemia virus (GALV-GP-R–) and human granulocyte-macrophage colony-stimulating factor (GM-CSF), and has its

  7. Drug

    Risvutatug rezetecan

    go.drugbank.com/drugs/DB23560
    Investigational

    Risvutatug rezetecan (GSK5764227) is a novel investigational B7-H3-targeted antibody-drug conjugate. … It is under investigation in clinical trial NCT06885034 (A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers

  8. Drug

    WNY0824

    go.drugbank.com/drugs/DB23606
    Experimental

    WNY0824 is a preclinical small molecule drug being investigated for the treatment of Castration-Resistant Prostrate Cancer (CRPC). … [A274253] It is a dual inhibitor of PLK-1 and BRET-4, which have both been found to be involved in CRPC via suppression of AR/MYC-mediated transcription. [A274258]

  9. Drug

    Actinium Ac 225 Vipivotide tetraxetan

    go.drugbank.com/drugs/DB23637
    Investigational

    Actinium Ac 225 Vipivotide Tetraxetan is a small molecule drug.

  10. Drug

    Arlocabtagene autoleucel

    go.drugbank.com/drugs/DB24024
    Investigational

    Arlocabtagene Autoleucel is a biologic drug. … Arlocabtagene Autoleucel is under investigation in clinical trial NCT06297226 (Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or