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Displaying results 761 - 770 of 10000 in total
  1. Drug

    Abatacept

    go.drugbank.com/drugs/DB01281
    ApprovedInvestigational

    [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each … It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes.

    Products: ORENCIA Injection 125mg/ml in Prefilled Syringe
  2. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.

    Products: MIRTAZAPINA DOC GENERICI, MIRTAZAPINA MYLAN GENERICS
  3. Drug

    Piroxicam

    go.drugbank.com/drugs/DB00554
    ApprovedInvestigational

    A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea … Its long half-life enables it to be administered once daily.

    Synonyms: 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxidProducts: STOPEN® INYECTABLE DE 20 MG, FELDENE INTRAMUSCULAR DE 20MG
  4. Drug

    Garcinia gummi-gutta fruit

    go.drugbank.com/drugs/DB14365
    Investigational

    Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Ari S-LinerProducts: Ari S-Liner
  5. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site.

    Products: TETRACICLINA DE 500 MG CAPSULAS, TETRACICLINA CAPSULAS DE 250 MG
  6. Drug

    Isoprenaline

    go.drugbank.com/drugs/DB01064
    ApprovedInvestigational

    Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion … [A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and cardiac output, without vasoconstriction

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N-Isopropylnoradrenaline, N-Isopropylnorepinephrine
  7. Drug

    Chlorpheniramine

    go.drugbank.com/drugs/DB01114
    ApprovedInvestigational

    A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. … One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.

    Mixtures: De-Chlor DM, Maux De Gorge Et De LA Toux Extra-fortSynonyms: 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine, 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine
  8. Drug

    Carvedilol

    go.drugbank.com/drugs/DB01136
    ApprovedInvestigational

    [L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the … Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.

    Categories: Compounds used in a research, industrial, or household settingProducts: CARVEDILOLO DOC GENERICI, CARVEDILOLO MYLAN GENERICS
  9. Drug

    Clopidogrel

    go.drugbank.com/drugs/DB00758
    ApprovedInvestigational

    in recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.

    Products: CLOPIDOGREL MYLAN GENERICS, CLOPIDOGREL DOC GENERICI
  10. Drug

    Treprostinil

    go.drugbank.com/drugs/DB00374
    ApprovedInvestigational

    [L41860] It is available in the following routes of administration: subcutaneous, intravenous, inhaled and oral. The first generic form of treprostinil became available in 2019.[A248775] … Treprostinil was approved by the FDA in 2002 for the treatment of pulmonary arterial hypertension.

    Mixtures: Tyvaso DPI, Tyvaso DPICategories: Prostaglandins I