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Displaying results 761 - 770 of 10000 in total
  1. Drug

    Nortriptyline

    go.drugbank.com/drugs/DB00540
    ApprovedInvestigational

    Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA). … [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881]

    Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin 5-HT1 Receptor AntagonistsSynonyms: 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine
  2. Drug

    (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE

    go.drugbank.com/drugs/DB07604
    Experimental

    Synonyms: (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE
  3. Drug

    N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE

    go.drugbank.com/drugs/DB07334
    Experimental

    Synonyms: N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE
  4. Drug

    N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide

    go.drugbank.com/drugs/DB07833
    Experimental

    Synonyms: N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide
  5. Drug

    Sparfloxacin

    go.drugbank.com/drugs/DB01208
    ApprovedWithdrawn

    Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase.

    Synonyms: cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acidCategories: 4-Quinolones, P-glycoprotein substrates
  6. Drug

    Thymidine monophosphate

    go.drugbank.com/drugs/DB01643
    Investigational

    5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-deoxy-5-methyluridine 5'-(dihydrogen phosphate), 5'-TMP
  7. Drug

    Flurocitabine

    go.drugbank.com/drugs/DB20317
    Experimental

    Flurocitabine is a small molecule drug. … Flurocitabine has a monoisotopic molecular weight of 243.07 Da.

    Synonyms: 5-fluorocyclocytidine, 5'-fluorocyclocytidine
  8. Drug

    Uridine monophosphate

    go.drugbank.com/drugs/DB03685
    Investigational

    5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.

    Synonyms: 5'-uridylic acid, Uridine 5'-monophosphateCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Aprobarbital

    go.drugbank.com/drugs/DB01352
    ExperimentalIllicit

    Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. … A primary treatment indicated for the use of aprobarbital was subsequently insomnia.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InducersSynonyms: 5-(1-methylethyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-isopropylpyrimidine-2,4,6(1H,3H,5H)-trione
  10. Drug

    (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3-thiazol-4-one

    go.drugbank.com/drugs/DB08710
    Experimental

    Synonyms: (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3-thiazol-4-one