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R450
go.drugbank.com/drugs/DB05469ExperimentalR450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. It is being considered for treatment of stress-related urinary incontinence. … Phase IIa data for the drug show it reduced the number of incontinent episodes compared to placebo with minimal cardiovascular effects.
Coltuximab ravtansine
go.drugbank.com/drugs/DB06342InvestigationalColtuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic leukemia (ALL).
ONO-8539
go.drugbank.com/drugs/DB15325InvestigationalONO-8539 is under investigation in clinical trial NCT01707901 (A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease).
4-Hydroxytestosterone
go.drugbank.com/drugs/DB01485IllicitInvestigational4-Hydroxytestosterone is testosterone substituted with a hydroxy group on the fourth carbon atom. … Formestane (Lentaron) acts as a prohormone of 4-Hydroxytestosterone, as 4-Hydroxytestosterone is one of the many byproducts of formestane metabolism.
Synonyms: 4-Androstene-7alpha-17beta-diol-3-one, 4,17beta-Dihydroxy-4-androstene-3-oneGestonorone
go.drugbank.com/drugs/DB13230ExperimentalGestonorone is often mistaken for gestonorone capproate which has a different chemical structure.
Categories: Sex Hormones and Modulators of the Genital SystemClinafloxacin
go.drugbank.com/drugs/DB14025ExperimentalHowever, its approval and release have been halted due to the presence of serious side effects.
Glibornuride
go.drugbank.com/drugs/DB08962ApprovedWithdrawnGlibornuride is a sulfonylurea-type anti-diabetic drug.
Categories: Drugs Used in DiabetesZoracopan
go.drugbank.com/drugs/DB21702InvestigationalZoracopan has a monoisotopic molecular weight of 614.16 Da. … The usage of the INN stem '-copan' in the name indicates that Zoracopan is a complement receptor antagonist/complement inhibitor.
AS1409
go.drugbank.com/drugs/DB05182InvestigationalIt is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and melanoma. … AS1409 is a genetically engineered fusion protein made up of two distinct components. One is the cytokine IL12, which has anti-cancer activity. The other is an antibody that targets tumours.
Revexepride
go.drugbank.com/drugs/DB20324InvestigationalRevexepride has a monoisotopic molecular weight of 425.21 Da. … The usage of the INN stem '-pride' in the name indicates that Revexepride is a sulpiride derivative and analogue.