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rAAV9-rsATP7A
go.drugbank.com/drugs/DB17664ExperimentalA recombinant adeno-associated viral vector gene therapy under investigation for the treatment of Menkes disease.
Avotermin
go.drugbank.com/drugs/DB11955InvestigationalJuvista has been investigated for the treatment, prevention, and basic science of Scars, Keloid, and Cicatrix.
Bradykinin
go.drugbank.com/drugs/DB12126InvestigationalBradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.
Irosustat
go.drugbank.com/drugs/DB02292InvestigationalIrosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Synonyms: 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-SulfamateAstegolimab
go.drugbank.com/drugs/DB16386InvestigationalAstegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
RTN-001
go.drugbank.com/drugs/DB05615InvestigationalSLx-2101 is an oral, long-acting PDE5 inhibitor developed by Surface Logix Inc. to treat Hypertension.
KBP-COVID-19
go.drugbank.com/drugs/DB15858InvestigationalKBP cloned COVID-19’s genetic sequence, identified a potential antigen, and then inserted it into tobacco plants for reproduction. … As of July 2020, KBP is conducting a Phase 1/2 clinical trial to evaluate the safety and immunogenicity of KBP-COVID-19 vaccine in healthy patients (NCT04473690).
OTOF-GT
go.drugbank.com/drugs/DB18129InvestigationalOTOF-GT is a dual vector AAV gene therapy being investigated for the restoration of hearing loss associated with otoferlin deficiency.
Tarcocimab tedromer
go.drugbank.com/drugs/DB18937InvestigationalTarcocimab tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately … Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)).
Synonyms: 240-alanine,241-alanine,243-alanine,449-cysteine], anti-(human vascular endothelial growth factor A) (human-Mus musculus monoclonal OG1950 g1-chain), disulfide with human-Mus musculus monoclonal OG1950 k-chainIsaralgagene civaparvovec
go.drugbank.com/drugs/DB16808InvestigationalIsaralgagene civaparvovec, formerly known as ST-920, is liver-tropic rAAV 2/6 vector carrying the cDNA for human alpha-galactosidase A (α-Gal A) enzyme. … It is developed by Sangamo Therapeutics and investigated in Fabry Disease.