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Displaying results 7711 - 7720 of 10000 in total
  1. Drug

    Ocedurenone

    go.drugbank.com/drugs/DB21519
    Investigational

    Ocedurenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Ocedurenone has a monoisotopic molecular weight of 503.21 Da.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    Brimarafenib

    go.drugbank.com/drugs/DB21706
    Investigational

    Brimarafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Brimarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. … Brimarafenib has a monoisotopic molecular weight of 482.12 Da.

  3. Drug

    XC221

    go.drugbank.com/drugs/DB16503
    Investigational

    XC221 was investigated in clinical trials to treat patients with respiratory infections, including influenza, COVID-19, and other acute viral upper respiratory infections.

  4. Drug

    Contusugene ladenovec

    go.drugbank.com/drugs/DB05322
    Investigational

    INGN 201(Advexin) is a replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and clinical trials. … Advexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in combination with radiation and/or chemotherapy agents.

  5. Drug

    FRAX716

    go.drugbank.com/drugs/DB31795
    Experimental

    FRAX716 is a group I-specific p21-activated kinase (PAK) inhibitor which dramatically inhibits the phosphorylation of PAK and Mek1.[A274678]

  6. Drug

    DP-b99

    go.drugbank.com/drugs/DB05820
    Investigational

    DP-b99 is a newly developed lipophilic, cell permeable derivative of BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), that is under development as a neuroprotectant for the potential treatment

  7. Drug

    Ethyl pyruvate

    go.drugbank.com/drugs/DB05869
    Investigational

    CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. … CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.

    Synonyms: Ethyl 2-oxopropanoate, Ethyl 2-oxopropionate
  8. Drug

    CIGB-258 peptide

    go.drugbank.com/drugs/DB15809
    Experimental

    CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular variant. … As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens

  9. Drug

    Alteminostat

    go.drugbank.com/drugs/DB19620
    Investigational

    Alteminostat is a small molecule drug. The usage of the INN stem '-inostat' in the name indicates that Alteminostat is a histone deacetylase inhibitor. … Alteminostat has a monoisotopic molecular weight of 492.28 Da.

  10. Drug

    Gemilukast

    go.drugbank.com/drugs/DB19882
    Investigational

    Gemilukast is a small molecule drug. The usage of the INN stem '-lukast' in the name indicates that Gemilukast is a leukotriene receptor antagonist. … Gemilukast is under investigation in clinical trial NCT01536041 (A Placebo and Active Controlled Study of ONO-6950 in Asthmatic Patients). Gemilukast has a monoisotopic molecular weight of 601.26 Da.

    Categories: Heterocyclic Compounds, 2-Ring