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3-Acetylpyridine Adenine Dinucleotide
go.drugbank.com/drugs/DB03363ExperimentalIt is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Octopamine
go.drugbank.com/drugs/DB13251ExperimentalOctopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as of 2014.
Loprazolam
go.drugbank.com/drugs/DB13643ExperimentalIt is a positive modulator of GABA-A receptor that enhances the inhibitory neurotransmission. It is not an FDA-approved drug. … Loprazolam is recommended as a short-term therapy only, due to adverse events associated with the drug including dependence and withdrawal symptoms.
Paquinimod
go.drugbank.com/drugs/DB13118InvestigationalPaquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease. … The autoimmune attack affects several different organ systems and many patients suffer from serious secondary disease symptoms such as renal disorders as the disease progresses.
Navacaprant
go.drugbank.com/drugs/DB16068InvestigationalBTRX-335140 is under investigation in clinical trial NCT04221230 (Study in Major Depressive Disorder With BTRX-335140 vs Placebo).
Rovafovir etalafenamide
go.drugbank.com/drugs/DB14903InvestigationalRovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing
5-methoxy-N,N-dimethyltryptamine
go.drugbank.com/drugs/DB14010IllicitInvestigationalThis drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South America in religious and spiritual rituals. … 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties.
Rhenium re-188
go.drugbank.com/drugs/DB19267InvestigationalRhenium re-188 is under investigation in clinical trial NCT03458559 (Rhenium-188-hedp vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal Therapy).
Lisavanbulin
go.drugbank.com/drugs/DB15224InvestigationalLisavanbulin is under investigation in clinical trial NCT02895360 (Phase 1/2a Study of BAL101553 as 48-hour Infusions in Patients With Advanced Solid Tumors or Recurrent Glioblastoma).