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Displaying results 7721 - 7730 of 10000 in total
  1. Drug

    Ciltacabtagene autoleucel

    go.drugbank.com/drugs/DB16738
    ApprovedInvestigational

    [A245854] B-cell maturation antigen (BCMA) is a transmembrane glycoprotein member of the tumor necrosis factor receptor superfamily 17 (TNFRSF17) which is used as a biomarker for multiple myeloma. … Multiple myeloma is a malignancy involving the plasma cells of the bone marrow.

    Synonyms: Autologous bi-epitope BCMA-targeted CAR T-cells
  2. Drug

    Prolgolimab

    go.drugbank.com/drugs/DB16740
    Investigational

    Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors
  3. Drug

    CP-96345

    go.drugbank.com/drugs/DB16744
    Experimental

    Categories: Substance P, antagonists & inhibitors
  4. Drug

    Elivaldogene autotemcel

    go.drugbank.com/drugs/DB16746
    Approved

    Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. … [A243691] ALDP is a key protein that normally breaks down fatty substances in the body called very long-chain fatty acids (VLCFAs).

    International brands: Lenti-D
  5. Drug

    STF-31

    go.drugbank.com/drugs/DB16761
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Tyrphostin B44

    go.drugbank.com/drugs/DB16762
    Experimental

    Synonyms: Tyrphostin B-44Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Morin

    go.drugbank.com/drugs/DB16770
    Experimental

    Synonyms: 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-one, Natural yellow 8Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    Rhamnetin

    go.drugbank.com/drugs/DB16772
    Experimental

    Synonyms: 7-O-Methylquercetin, 7-MethoxyquercetinCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    Resamirigene bilparvovec

    go.drugbank.com/drugs/DB16779
    Investigational

    AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).

    Synonyms: DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying), Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin gene
  10. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes

    Synonyms: EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA), A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS