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Redasemtide
go.drugbank.com/drugs/DB19121InvestigationalRedasemtide is under investigation in clinical trial NCT05953480 (A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke).
ALT001
go.drugbank.com/drugs/DB33989ExperimentalALT001 is under investigation in clinical trial NCT07833618 (A Phase II Study of ALT001 in Patients With Amyotrophic Lateral Sclerosis (ALS)).
Romifidine
go.drugbank.com/drugs/DB11543ExperimentalVet approvedRomifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species. … This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved for use in humans.
SARS-CoV-2 Sclamp
go.drugbank.com/drugs/DB15849InvestigationalAs of July 13, 2020, the candidate is being tested for safety and immunogenicity in Phase 1 clinical trials in Queensland (ACTRN12620000674932). … The vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine platform that locks surface proteins in a configuration that allows more robust immune responses, in combination with a well-established
UB-612
go.drugbank.com/drugs/DB16444InvestigationalIt was able to reduce viral load and prevent COVID-19 infection in a mouse challenge model and in rhesus macaques[L30653, L30658]. … In rats, toxicity studies have so far shown favourable safety for this vaccine[L30653, L30658], Phase 1 trial is currently ongoing in Taiwan (NCT04545749).
LCP-AtorFen
go.drugbank.com/drugs/DB05769InvestigationalLCP-AtorFen is a fixed-dose combination therapy for the treatment of high cholesterol levels combining atorvastatin (the active ingredient of Lipitor®) and the lowest dose of fenofibrate without food effect. LCP-AtorFen is designed to be...
CVT-6883
go.drugbank.com/drugs/DB05936ExperimentalCVT-6883 is a selective, potent and orally available A2B-adenosine receptor antagonist which CV Therapeutics is investigating for the potential treatment of asthma and other conditions related to inflammation and fibrosis.