Thrombopoietin
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Thrombopoietin
- DrugBank Accession Number
- DB06534
- Background
Not Available
- Type
- Biotech
- Groups
- Investigational
- Biologic Classification
- Protein Based Therapies
Other protein based therapies - Protein Chemical Formula
- Not Available
- Protein Average Weight
- Not Available
- Sequences
- Not Available
- Synonyms
- Not Available
Pharmacology
- Indication
Investigated for use/treatment in thrombocytopenia.
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- Pharmacodynamics
Not Available
- Mechanism of action
Target Actions Organism UThrombopoietin receptor Not Available Humans - Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareCyclophosphamide The risk or severity of pulmonary toxicity can be increased when Thrombopoietin is combined with Cyclophosphamide. Vinblastine The risk or severity of peripheral neuropathy can be increased when Thrombopoietin is combined with Vinblastine. Vincristine The risk or severity of peripheral neuropathy can be increased when Thrombopoietin is combined with Vincristine. Vindesine The risk or severity of peripheral neuropathy can be increased when Thrombopoietin is combined with Vindesine. Vinflunine The risk or severity of peripheral neuropathy can be increased when Thrombopoietin is combined with Vinflunine. - Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- Not Available
- Kingdom
- Organic Compounds
- Super Class
- Organic Acids
- Class
- Carboxylic Acids and Derivatives
- Sub Class
- Amino Acids, Peptides, and Analogues
- Direct Parent
- Peptides
- Alternative Parents
- Not Available
- Substituents
- Not Available
- Molecular Framework
- Not Available
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 5651J3R2JF
- CAS number
- 9014-42-0
References
- General References
- Not Available
- External Links
- Wikipedia
- Thrombopoietin
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Treatment Neoplasms, Gynecologic 1 somestatus stop reason just information to hide Not Available Recruiting Not Available Autoimmune Hemolytic Anemia / Autoimmune Neutropenia / Chronic Idiopathic Neutropenia / Cold Agglutinin Disease (CAD) / Immune Thrombocytopenia (ITP) / Myelodysplastic Syndrome 1 somestatus stop reason just information to hide Not Available Unknown Status Not Available Hemostatic Disorders 1 somestatus stop reason just information to hide Not Available Unknown Status Not Available Immune Thrombocytopenia (ITP) 1 somestatus stop reason just information to hide 4 Completed Treatment Aplastic Anemia 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
Targets
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1. DetailsThrombopoietin receptor
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent immune responses
- Specific Function
- thrombopoietin receptor activity
- Gene Name
- MPL
- Uniprot ID
- P40238
- Uniprot Name
- Thrombopoietin receptor
- Molecular Weight
- 71244.08 Da
Drug created at March 19, 2008 16:36 / Updated at June 12, 2020 16:52