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Displaying results 7731 - 7740 of 10000 in total
  1. Drug

    Becotatug vedotin

    go.drugbank.com/drugs/DB17407
    Investigational

    MRG-003 is a recombinant humanized anti-human epidermal growth factor receptor monoclonal antibody conjugated to monomethyl auristatin E.

  2. Drug

    KITE-585

    go.drugbank.com/drugs/DB17409
    Investigational

    KITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy. It is being investigated in the treatment of multiple myeloma.

  3. Drug

    TNG908

    go.drugbank.com/drugs/DB17411
    Investigational

    TNG908 is a small molecule inhibitor of protein arginine methyl transferase 5 (PRMT5).

  4. Drug

    SCH-58500

    go.drugbank.com/drugs/DB17416
    Investigational

    SCH-58500 is a recombinant replication-deficient adenovirus vector carrying the human p53 gene.

  5. Drug

    MT-0169

    go.drugbank.com/drugs/DB17430
    Investigational

    MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to a human single chain variable fragment with affinity for human CD38 cell surface protein.

  6. Drug

    EU204

    go.drugbank.com/drugs/DB17438
    Investigational

    EU204 (EBViNT) is an Epstein-Barr virus (EBV)-positive T-cell therapy currently undergoing phase 1 and 2a clinical trials in Korea for patients with EBV-positive lymphoma and solid cancer.

    Synonyms: EBV-induced natural T cell [EBViNT Cell]
  7. Drug

    Allovectin-7

    go.drugbank.com/drugs/DB17439
    Investigational

    Allovectin-7 or allovectin-7(r) is a lipid complex that contains the DNA sequences encoding HLA-B7 and beta-2 microglobulin.

    Synonyms: Allovectin-7(r), Allovectin-7
  8. Drug

    Lym-1-I-131

    go.drugbank.com/drugs/DB17445
    Experimental

    Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.

    Synonyms: Monoclonal antibody LYM-1-I-131, Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma
  9. Drug

    Linvoseltamab

    go.drugbank.com/drugs/DB17447
    ApprovedInvestigational

    Linvoseltamab (INN), marketed as Lynozyfic™, is a bispecific human IgG4 monoclonal antibody developed by Regeneron that promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma … This mechanism results in the targeted release of cytokines such as IL-2, IL-6, and IFN-gamma, promoting the selective lysis of BCMA-expressing cells and offering a novel immunotherapeutic approach for

    Synonyms: human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMACategories: Bispecific B Cell Maturation Antigen-directed CD3 T Cell Engager
  10. Drug

    Tusamitamab ravtansine

    go.drugbank.com/drugs/DB17448
    Investigational

    Tusamitamab ravtansine is an antibody-drug conjugate that targets carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5).