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Chelerythrine

A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.

Alphaprodine

Nalfurafine

Cerulenin

Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. … In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity.

Plosaracetam

Plosaracetam has a monoisotopic molecular weight of 330.05 Da. … The usage of the INN stem '-racetam' in the name indicates that Plosaracetam is a piracetam type amide type nootrope agent.

Atirmociclib

Atirmociclib has a monoisotopic molecular weight of 463.18 Da. … The usage of the INN stem '-ciclib' in the name indicates that Atirmociclib is a cyclin dependant kinase inhibitor.

MLN0415

In preclinical studies, MLN0415 was shown to decrease NF-kB activation and down-regulate the expression of a number of inflammatory proteins. … Because inflammatory proteins play a critical role in inflammation and drive the inflammatory response to disease, controlling these proteins may prevent or slow disease progression.

Streptococcus pneumoniae type 9N capsular polysaccharide diphtheria CRM197 protein conjugate antigen

_ serotype 9N individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of _Corynebacterium diphtheriae_ strain C7 (β197). … Streptococcus pneumoniae type 9N capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of _Streptococcus pneumoniae

24-Homo-1,25-dihydroxyvitamin D3

24-Homo-1,25-dihydroxyvitamin D3 is a novel [vitamin D] analogue.

Theralizumab

After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]