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Fianlimab
go.drugbank.com/drugs/DB18858InvestigationalFianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or
Cofirasersen
go.drugbank.com/drugs/DB19037InvestigationalCofirasersen is under investigation in clinical trial NCT04441788 (A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary
ARI-0001
go.drugbank.com/drugs/DB30635InvestigationalARI-0001 is under investigation in clinical trial NCT05641428 (Comparison of Point-of-care Produced CAR T-cell with Commercial CAR T-cells in Patients with R/R LBCL).
Amniotic membrane
go.drugbank.com/drugs/DB33970ExperimentalAmniotic membrane is under investigation in clinical trial NCT07824596 (The Role of Amniotic Membrane in Promoting Rapid Recovery of Buccal Mucosal Defect After Harvesting Oral Mucosa for Urethral Reconstruction
Alpha-galactosylceramide
go.drugbank.com/drugs/DB12232InvestigationalKRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With
Synonyms: 1-O-(α-D-galactopyranosyl)-N-hexacosanoylphytosphingosineSagopilone
go.drugbank.com/drugs/DB12391Investigationalmultidrug-resistant and paclitaxel-resistant tumor cell lines in vitro and in vivo. … Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others.
Reparixin
go.drugbank.com/drugs/DB12614Investigational1, and Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus. … Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type
Enpatoran
go.drugbank.com/drugs/DB16501InvestigationalIt was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327). … Enpatoran (M5049) was under investigation in clinical trials for various conditions.
Tyrosinase
go.drugbank.com/drugs/DB16626InvestigationalTyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states. … [A231829, A231834, A231839] Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis (also known