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AP103
go.drugbank.com/drugs/DB18234ExperimentalAP103 is a non-viral gene therapy that uses a delivery vector, HPAE (Highly Branched Poly β-Amino Ester), to deliver the correct collagen VII gene into skin cells.
Nerandomilast
go.drugbank.com/drugs/DB18237ApprovedInvestigationalNerandomilast is a phosphodiesterase 4 (PDE4) inhibitor that preferentially inhibits the PDE4B subtype. It has one chiral center and is the R-stereoisomer. … [L54126] On October 7, 2025, nerandomilast was approved as the first new treatment for idiopathic pulmonary fibrosis in more than a decade.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsAMP-101
go.drugbank.com/drugs/DB18253ExperimentalAMP-101 is a gene therapy comprising an adeno-associated virus type 9 (AAV9) vector encoding the human Dok-7 protein. It is under investigation for the treatment of Dok-7-associated myasthenia.
Synonyms: Adeno-associated virus serotype 9 vector encoding the Dok7 proteinDCN-tCRK
go.drugbank.com/drugs/DB18262ExperimentalDCN-tCRK is a recombinant, multi-functional fusion protein consisting of human decorin fused to the C-terminal vascular homing peptide tCRK.
HM15912
go.drugbank.com/drugs/DB18266InvestigationalHM15912 is a human glucagon-like peptide-2 analogue linked to a human immunoglobulin Fc fragment.
TAK-075 Free base
go.drugbank.com/drugs/DB18268ExperimentalSynonyms: Pyrazolo(1,5-a)pyrimidine-3-carboxamide, n-(1-ethyl-1-(4-ethylphenyl)propyl)-4,5,6,7-tetrahydro-2,7,7-trimethyl-5-phenyl-, (5r)-Categories: Heterocyclic Compounds, 1-RingOptPA
go.drugbank.com/drugs/DB18325ExperimentalOptimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.[A261486]
ATA-100
go.drugbank.com/drugs/DB18329InvestigationalATA-100 is an adeno-associated virus serotype 9 carrying the human Fukutin-Related protein gene and target sequence of the miR-208a
TLY-012
go.drugbank.com/drugs/DB18336ExperimentalTLY-012 is a PEGylated recombinant human tumor necrosis factor-related apoptosis-inducing ligand (PEGylated TRAIL).[L48166]
GS-100
go.drugbank.com/drugs/DB18337InvestigationalGS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression cassette containing the human NGLY1 gene coding sequence