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Ondelopran
go.drugbank.com/drugs/DB12585InvestigationalOndelopran has been used in trials studying the treatment of Alcohol Dependence.
Categories: Heterocyclic Compounds, 1-RingRazupenem
go.drugbank.com/drugs/DB12587InvestigationalRazupenem has been used in trials studying the treatment of Skin Infections.
Categories: Heterocyclic Compounds, 2-RingPF-477736
go.drugbank.com/drugs/DB12611InvestigationalPF-00477736 has been used in trials studying the treatment of Neoplasms.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingGinkgolide A
go.drugbank.com/drugs/DB06743ExperimentalNutraceuticalGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
Synonyms: Ginkgolide-AGonyautoxin III
go.drugbank.com/drugs/DB19187ExperimentalGonyautoxin III is currently under investigation in clinical trial (Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study) for the treatment of Acute Back Pain.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 1h,10h-pyrrolo(1,2-c)purine-9,10,10-triol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, 9-(hydrogen sulfate), (3as-(3a.alpha.,4.alpha.,9.alpha.,10ar*))- 11-sulfate, (+)-gonyautoxin 3ABH001
go.drugbank.com/drugs/DB16177InvestigationalABH001 is under investigation in clinical trial NCT01749306 (A Study of the Efficacy and Safety of ABH001 in the Treatment of Patients With Epidermolysis Bullosa Who Have Wounds That Are Not Healing).
SBT-100
go.drugbank.com/drugs/DB17215ExperimentalIt was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136] … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb).
Synonyms: anti-STAT3 B VHH13, Anti-STAT3 B VHH13 single domain antibodyOmburtamab
go.drugbank.com/drugs/DB15635Investigational[A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers. … CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours.
ZD4407
go.drugbank.com/drugs/DB06539ExperimentalThe drug ZD4407, an antiasthmatic developed by AstraZeneca, functions as a 5-lipoxygenase inhibitor. … It entered Phase 1 clinical trials for chronic obstructive pulmonary disease (COPD) in the United Kingdom but was discontinued during this phase in March 2003
Synonyms: 1,3-DIHYDRO-1-METHYL-5-((4-((2S,4R)-TETRAHYDRO-4-HYDROXY-2-METHYL-2H-PYRAN-4-YL)-2-THIENYL)THIO)-2H-INDOL-2-ONE, 5-(4-((2S,4R)-4-HYDROXY-2-METHYLOXAN-4-YL)THIOPHEN-2-YL)SULFANYL-1-METHYL-3H-INDOL-2-ONESerrapeptase
go.drugbank.com/drugs/DB13131InvestigationalSerratiopeptidase is under investigation in clinical trial NCT02493179 (Efficacy Evaluation of the (Serodase 5 mg Tablet) in the Treatment of Inflammation After Third Molar Surgery). … Serrapeptase is a proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections.
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