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Cardiolipin Biosynthesis CL(i-14:0/i-24:0/i-24:0/25:0)
smpdb.ca/view/SMP0495470MetabolicCardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.
Cardiolipin Biosynthesis CL(i-15:0/i-24:0/i-24:0/25:0)
smpdb.ca/view/SMP0495476MetabolicCardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.
Cardiolipin Biosynthesis CL(i-12:0/17:0/i-21:0/i-22:0)
smpdb.ca/view/SMP0495479MetabolicCardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.
Cardiolipin Biosynthesis CL(15:0/i-16:0/i-19:0/i-24:0)
smpdb.ca/view/SMP0495563MetabolicCardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.
Pheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine's use as an anti-allergy medication has largely been supplanted by second-generation antihistamines such as [cetirizine] and [loratadine]. … Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine].
Mixtures: Bronchodex D Cap, Cold Decongestant Long Acting CapCategories: Heterocyclic Compounds, 1-RingTrolamine
go.drugbank.com/drugs/DB13747ApprovedInvestigationalTrolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. … Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and vegetable fats [A27174].
Synonyms: nitrilo-2,2',2''-triethanol, tris(2-hydroxyethyl)amineAmivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigational[A235133] Amivantamab was granted FDA approval on 21 May 2021,[L34193] followed by the approval by the EMA on 9 December 2021 [L41474] and Health Canada on 30 March 2022. … non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose disease has progressed on or after platinum-based
Norgestimate
go.drugbank.com/drugs/DB00957ApprovedInvestigational[A191068] It is commonly formulated with [ethinylestradiol] as a combined oral contraceptive that can also be used to treat moderate acne vulgaris. … [A191068] It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects.
Mixtures: TriNessa Lo, TriNessa LoCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCytochrome P450 2C12, female-specific
go.drugbank.com/bio_entities/BE0010015EnzymeRatThis P450 is active in 15-beta-hydroxylation of steroid sulfates.
Synonyms: Cytochrome P450-UT-IAbametapir
go.drugbank.com/drugs/DB11932ApprovedThe necessity for follow-up treatment may lead to challenges with patient adherence, and resistance to agents like permethrin and [pyrethrins]/[piperonyl butoxide] may be significant in some areas. … [A216178] Abemetapir is an inhibitor of these metalloproteinase enzymes, and the first topical pediculicide to take advantage of this novel target.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors