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Displaying results 7871 - 7880 of 10000 in total
  1. Drug

    Siplizumab

    go.drugbank.com/drugs/DB06371
    Investigational

  2. Drug

    Aptazapine

    go.drugbank.com/drugs/DB09305
    Experimental

    It antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5-HT2 receptors, agonised H1 receptors, and did not affect reuptake of serotonin or norepinephrine … Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity.

  3. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. … Developed by Sangamo Therapeutics, tefidsogene civaparvovec is being investigated in mucopolysaccharidosis type II.[A258789, L45949]

    Synonyms: A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS
  4. Drug

    Tyrosol

    go.drugbank.com/drugs/DB16855
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Mebhydrolin

    go.drugbank.com/drugs/DB13808
    Investigational

    Mebhydrolin is an antihistamine agent.[A275123]

    Categories: Antihistamines for Systemic Use
  6. Drug

    Clofoctol

    go.drugbank.com/drugs/DB13237
    Experimental

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  7. Drug

    Guanosine

    go.drugbank.com/drugs/DB02857
    Investigational

    Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. … Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate) which are factors in signal

  8. Drug

    Tenitramine

    go.drugbank.com/drugs/DB13637
    Experimental

    Categories: Vasodilators Used in Cardiac Diseases
  9. Drug

    Ociperlimab

    go.drugbank.com/drugs/DB18947
    Investigational

    Ociperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage … III Unresectable Non-small Cell Lung Cancer).

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens tigit (t-cell immunoreceptor with ig domain and itim, v-set ig member 9, vsig9, v-set and transmembrane member 3, vstm3)), humanized monoclonal antibody (ociperlimab
  10. Drug

    Dextromoramide

    go.drugbank.com/drugs/DB01529
    ExperimentalIllicit

    An opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome