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Pegilodecakin
go.drugbank.com/drugs/DB15162InvestigationalPegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small
Synonyms: INTERLEUKIN 10 (SYNTHETIC HUMAN), DIMER, N-TERMINAL 5-KILODALTON PEGYLATEDElezanumab
go.drugbank.com/drugs/DB15240InvestigationalElezanumab is under investigation in clinical trial NCT03737812 (A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis).
Afabicin
go.drugbank.com/drugs/DB15268InvestigationalAfabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus
Lulizumab pegol
go.drugbank.com/drugs/DB15441InvestigationalLulizumab pegol is under investigation in clinical trial NCT02843659 (Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome).
Vezocolmitide
go.drugbank.com/drugs/DB21751InvestigationalVezocolmitide is under investigation in clinical trial NCT06178679 (Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease
Gam-COVID-Vac
go.drugbank.com/drugs/DB15848InvestigationalJune 2020, and were completed in early August 2020. … Gam-COVID-Vac was created by Gamaleya Research Institute of Epidemiology and MIcrobiology in Russia.
Defoslimod
go.drugbank.com/drugs/DB20763InvestigationalDefoslimod is under investigation in clinical trial NCT01800812 (Effects of OM-174 in Adult Patients With Solid Tumors). Defoslimod has a monoisotopic molecular weight of 1148.65 Da. … The usage of the INN stem '-imod' in the name indicates that Defoslimod is a immunomodulator, both stimulant/suppressive and stimulant.
Empesertib
go.drugbank.com/drugs/DB19473InvestigationalEmpesertib is under investigation in clinical trial NCT02138812 (Phase I Dose Escalation of Oral BAY1161909 in Combination With Intravenous Paclitaxel). … The usage of the INN stem '-sertib' in the name indicates that Empesertib is a serine/threonine kinase inhibitor.
Ancremonam
go.drugbank.com/drugs/DB19710InvestigationalAncremonam is under investigation in clinical trial NCT03377426 (LYS228 PK, Clinical Response, Safety and Tolerability in Patients With Complicated Urinary Tract Infection (cUTI)). … The usage of the INN stem '-monam' in the name indicates that Ancremonam is a monobactam antibiotic.
Mevociclib
go.drugbank.com/drugs/DB21454InvestigationalMevociclib is under investigation in clinical trial NCT03134638 (A Study of SY-1365 in Adult Patients With Advanced Solid Tumors). Mevociclib has a monoisotopic molecular weight of 586.26 Da. … The usage of the INN stem '-ciclib' in the name indicates that Mevociclib is a cyclin dependant kinase inhibitor.