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Displaying results 7881 - 7890 of 10000 in total
  1. Drug

    HMR4011

    go.drugbank.com/drugs/DB06225
    Experimental

    HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid. … IPL 576,092 has previously been investigated as a treatment for asthma.

  2. Drug

    SYN-101

    go.drugbank.com/drugs/DB05958
    Experimental

    SYN-101 is an investigational antibody-drug conjugate developed for the treatment of cancer. … SYN101 is comprised of an immune cell specific antibody linked to an ALK5 inhibitor payload to selectively block TGF-b signalling in immune cells.

  3. Drug

    Prasterone sulfate

    go.drugbank.com/drugs/DB05804
    Investigational

    DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin.

    Synonyms: 3-O-Sulfodehydroepiandrosterone, Androst-5-en-17-on-3beta-yl sulfuric acid
  4. Drug

    Treamid

    go.drugbank.com/drugs/DB16365
    Investigational

    Treamid, also known as bisamide derivative of dicarboxylic acid (BDDA), is a complexing agent that has been found to chelate metal ions, including calcium, copper, iron, magnesium, and zinc. … and Safety of Treamid in the Rehabilitation of Patients After COVID-19 Pneumonia) by PHARMENTERPRISES.

    Synonyms: Bisamide derivative of dicarboxylic acid
  5. Drug

    Ocriplasmin

    go.drugbank.com/drugs/DB08888
    ApprovedWithdrawn

    Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012.

  6. Drug

    Trodusquemine

    go.drugbank.com/drugs/DB06333
    Investigational

    Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits protein tyrosine phosphatase 1B. … It has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models [A176600].

  7. Drug

    Hydroxyprogesterone

    go.drugbank.com/drugs/DB14570
    Investigational

    Synonyms: Pregn-4-ene-3,20-dione-17-ol, delta(4)-Pregnene-17alpha-ol-3,20-dioneCategories: Sex Hormones and Modulators of the Genital System
  8. Drug

    Iprindole

    go.drugbank.com/drugs/DB13496
    Experimental

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  9. Drug

    Quingestanol

    go.drugbank.com/drugs/DB13685
    Experimental

    Categories: Sex Hormones and Modulators of the Genital System
  10. Drug

    DTX-101

    go.drugbank.com/drugs/DB17699
    Investigational

    DTX-101 is an investigational gene therapy consisting of an adeno-associated virus serotype Rh10 vector encoding the human Factor Ix gene. … It was previously investigated for the treatment of hemophilia B; however, the clinical development of DTX-101 was discontinued.[L46103]