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Displaying results 781 - 790 of 8696 in total
  1. Drug

    OriCar-017

    go.drugbank.com/drugs/DB17280
    Investigational

    Synonyms: chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D (GPRC5D)
  2. Drug

    Mitoxantrone

    go.drugbank.com/drugs/DB01204
    ApprovedInvestigational

    An anthracenedione-derived antineoplastic agent.

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: MITOXANTRONE BAXTER SOLUTION FOR INJECTION 20MG/10ML (2MG/ML), Ebexantron 2 mg/ml - Konzentrat zur Herstellung einer Infusionslösung
  3. Drug

    Midazolam

    go.drugbank.com/drugs/DB00683
    ApprovedIllicitInvestigational

    [L45098] In May 2019, the nasal spray of midazolam was approved for the acute treatment of distinctive intermittent, stereotypic seizure episodes in patients 12 years of age and older. … [F2977] This drug was initially approved by the US FDA in 1985, and has been approved for various indications since.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: MIDAZOLAM-BAXTER SOLUTION FOR INJECTION 1 MG/ML, MIDAZOLAM-BAXTER SOLUTION FOR INJECTION 5 MG/ML
  4. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    affinity-enhanced T cell receptor (TCR) specific for the human MAGE-A4. … [L51114] MAGE-A4 is an intracellular cancer-testis antigen that is overexpressed by cancer cells in synovial sarcoma.

    Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE
  5. Drug

    ARGX-119

    go.drugbank.com/drugs/DB18133
    Investigational

    ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).

    Synonyms: a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and activates MuSK
  6. Drug

    Apixaban

    go.drugbank.com/drugs/DB06605
    ApprovedInvestigational

    Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Mar-apixaban
  7. Drug

    Tenofovir disoproxil

    go.drugbank.com/drugs/DB00300
    ApprovedInvestigational

    This drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: TENOFOVIRDISOPROXIL PU 245
  8. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    It is an anthranilic acid derivative. … In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients

    Categories: Antihypertensive Agents Indicated for HypertensionProducts: Furon 250 mg - Konzentrat zur Infusionsbereitung, FUROSEMIDE-BAXTER SOLUTION FOR INJECTION 50 MG/5 ML
  9. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    patients may require for surgery. … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery.

    Products: BRIDION 100MG/ML SOLUTION FOR INJECTION, Bridion Solution For Injection 100mg/ml
  10. Drug

    Dipyridamole

    go.drugbank.com/drugs/DB00975
    ApprovedInvestigational

    A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 199...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Dipyridamole for Injection