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ISTH0036
go.drugbank.com/drugs/DB18606InvestigationalISTH0036 is a synthetic 14-mer phosphorothioate antisense oligonucleotide directed against TGF-beta2 mRNA
BVX-001
go.drugbank.com/drugs/DB18733ExperimentalBVX001 is a a novel, first-in-class CD33/CD7-directed antibody-drug conjugate.
AZD-7268
go.drugbank.com/drugs/DB19203InvestigationalAZD-7268 is under investigation in clinical trial NCT01020799 (AZD7268 Safety and Tolerability Study).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Benzamide, n-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-, N-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-benzamideOXB-301
go.drugbank.com/drugs/DB19269InvestigationalOXB-301 is under investigation in clinical trial NCT00397345 (Trovax Renal Immunotherapy Survival Trial).
7MW3711
go.drugbank.com/drugs/DB19298InvestigationalDeveloped by Mabwell, 7MW3711 is an antibody-drug conjugate targeting B7-H3.[L50918,L50923]
Nesvategrast
go.drugbank.com/drugs/DB19337InvestigationalNesvategrast is under investigation in clinical trial NCT05409235 (Nesvategrast (OTT166) in Diabetic Retinopathy (DR)).
Synonyms: (s)-3-(6-(difluoromethoxy)pyridin-3-yl)-3-(oxo-2-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoate, 3-Pyridinepropanoic acid, 6-(difluoromethoxy)-β-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]-, (βS)-Onfekafusp alfa
go.drugbank.com/drugs/DB16269InvestigationalOnfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Synonyms: Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion protein with human tumor necrosis factor .alpha., trimerTPCA-1
go.drugbank.com/drugs/DB17058ExperimentalTPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152]
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide, 3-thiophenecarboxamide, 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-CDX-6210
go.drugbank.com/drugs/DB17610ExperimentalCDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_.
Farampator
go.drugbank.com/drugs/DB15012InvestigationalFarampator is under investigation in clinical trial NCT00113022 (Org 24448 to Treat Major Depression).
Categories: Heterocyclic Compounds, 1-Ring