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Fluciclovine
go.drugbank.com/drugs/DB15237InvestigationalFluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).
Categories: P-glycoprotein inhibitorsSynonyms: Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid, Cyclobutanecarboxylic acid, 1-amino-3-fluoro-, trans-Idursulfase beta
go.drugbank.com/drugs/DB16190InvestigationalIdursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Synonyms: Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform beta)Cicletanine
go.drugbank.com/drugs/DB12766InvestigationalCicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
Categories: Heterocyclic Compounds, 1-RingTerpinen-4-ol
go.drugbank.com/drugs/DB12816InvestigationalTerpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesSynonyms: Terpinen-4-olGranotapide
go.drugbank.com/drugs/DB12934InvestigationalGranotapide has been used in trials studying the treatment of Type II Diabetes Mellitus.
Teclozan
go.drugbank.com/drugs/DB13205InvestigationalTeclozan is an antiprotozoal agent employed typically as a therapy to treat protozoan infections.
Products: FALMONOX ® TABLETASEnbucrilate
go.drugbank.com/drugs/DB12358InvestigationalEnbucrilate is under investigation in clinical trial NCT02468206 (Secondary Prophylaxis of Gastric Variceal Bleed).
Categories: Compounds used in a research, industrial, or household settingSynonyms: N-butyl-2-cyanoacrylate, Butyl 2-cyanoacrylateMYR-101
go.drugbank.com/drugs/DB17075InvestigationalIt is caused by a mutation in the aspartoacylase gene (_ASPA_), which leads to a deficiency of the aspartoacylase enzyme (ASPA). … ASPA is produced in oligodendrocytes, and participates in the metabolism of N-acetylaspartate (NAA).
CTx-PDE6b
go.drugbank.com/drugs/DB17858InvestigationalCTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human _PDE6b_ gene. … Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to _PDE6b_ gene mutations.[L46757]
Synonyms: AAV2/5-hPDE6BVY-HTT01
go.drugbank.com/drugs/DB16999InvestigationalVY-HTT01 is a gene therapy designed to reduce the expression of huntingtin, thereby altering disease progression. … VY-HTT01 is comprised of an adeno-associated virus capsid (AAV1) and a proprietary transgene that harnesses the canonical RNA interference pathway to selectively knock down levels of HTT mRNA.