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DSP107
go.drugbank.com/drugs/DB17501InvestigationalDSP107 is a bi-functional, trimeric, fusion protein composed of sequences from the extracellular domain of SIRPα and 4-1BBL.
SIS-101-ADO
go.drugbank.com/drugs/DB18085ExperimentalSIS-101-ADO is a siRNA therapeutic under investigation for the treatment of Autosomal Dominant Osteopetrosis Type 2 (ADO2).[L48091]
Xaluritamig
go.drugbank.com/drugs/DB18137InvestigationalXaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Synonyms: immunoglobulin G1-scFv-CH/G1-kappa, anti-[Homo sapiens STEAP1 (STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and anti-[Homo sapiens CD3, bispecificTSHA-105
go.drugbank.com/drugs/DB18328InvestigationalTSHA-105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human SLC13A5 protein.
RC118
go.drugbank.com/drugs/DB18428InvestigationalRC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
Synonyms: Recombinant humanized anti-MSLN monoclonal antibody- monomethyl auristatin E conjugateGYM329
go.drugbank.com/drugs/DB18590InvestigationalGYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Synonyms: recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent mannerTobevibart
go.drugbank.com/drugs/DB18986InvestigationalTobevibart is under investigation in clinical trial NCT05612581 (A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection).
AGI-134
go.drugbank.com/drugs/DB19005InvestigationalAGI-134 is under investigation in clinical trial NCT03593226 (Study to Evaluate Safety & Tolerability of AGI-134 in Solid Tumour).
JNJ-55308942
go.drugbank.com/drugs/DB19110InvestigationalJNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).
Mecapegfilgrastim
go.drugbank.com/drugs/DB19147InvestigationalMecapegfilgrastim is under investigation in clinical trial NCT05463601 (Mecapegfilgrastim for the Prevention of Dalpiciclib -Induced Neutropenia in Advanced Breast Cancer).