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Brivaracetam
go.drugbank.com/drugs/DB05541ApprovedInvestigationalBrivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184]. … Briviact received FDA approval on February 19, 2016 [L760].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: BRIVIACT ® 25 MG COMPRIMIDOS RECUBIERTOS., BRIVIACT 75 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLETLuspatercept
go.drugbank.com/drugs/DB12281ApprovedInvestigational[A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients with beta thalassemia who require regular blood … Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.
Products: Reblozyl 25 mg powder for solution for injection, Reblozyl 75 mg powder for solution for injectionDarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalIt is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments. … Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamideFluticasone propionate
go.drugbank.com/drugs/DB00588ApprovedInvestigationalFluticasone propionate was first approved in 1990[L5962]. … Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label].
Mixtures: SUN RHEORAN SF INHALER 25/250 mcg, SUN RHEORAN SF INHALER 25/125 mcgCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesUrofollitropin
go.drugbank.com/drugs/DB00094ApprovedVet approvedWithdrawnThe alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24. … Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human urine samples.
Mixtures: Fertinorm Hp 75 - Pws Diluent Im ScProducts: BRAVELLE 75 IU SC ENJEKSIYON ÇÖZELTI IÇEREN FLAKON VE ÇÖZÜCÜ IÇEREN AMPUL, 5 ADET, Fostimon 75 I.E. Pulver und Lösungsmittel zur Herstellung einer InjektionslösungTirzepatide
go.drugbank.com/drugs/DB15171ApprovedInvestigational[L48766] On September 15, 2022, tirzepatide was also approved by the European Commission.[L44386]. On November 02, 2023, tirzepatide was also approved by the Health Canada [L52800] … [A246265] Tirzepatide was approved by the FDA on May 13, 2022, under the brand name MOUNJARO by the FDA for the treatment of adults with type 2 diabetes, making it the first and only GIP and GLP-1 receptor
Categories: Receptors, G-Protein-Coupled, Drugs Used in DiabetesProducts: Mounjaro 5 mg solution for injection in vial, Mounjaro 5 mg solution for injection in pre-filled penCefprozil
go.drugbank.com/drugs/DB01150ApprovedInvestigationalCefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Categories: Heterocyclic Compounds, 2-RingProducts: CEFPROZIL ORCHID EUROPE, SEROL 250 MG/5 ML ORAL SÜSPANSIYON IÇIN TOZ ,60 MLRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalHowever there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … FDA approved on July 1, 2011.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: RIVAROXABAN SUN, RIBEX® 15 MGLevonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigational[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. … Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy.
Mixtures: AMESTRAL-25, CYCLO PROGYNOVA N 2MG/0.15Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNaproxen
go.drugbank.com/drugs/DB00788ApprovedInvestigationalVet approvedNaproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. … [A179098] Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia.
Synonyms: (+)-2-(6-Methoxy-2-naphthyl)propionic acid, (S)-2-(6-Methoxy-2-naphthyl)propanoic acidInternational brands: Bumaflex N, Proxen S