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Displaying results 791 - 800 of 10000 in total
  1. Drug

    Duvakitug

    go.drugbank.com/drugs/DB19444
    Investigational

    Duvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).

    Synonyms: gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-8*01 (92.9%) -(IGHD) -IGHJ4*01 (92.9%),CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119)-Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3, D12,L14 (CH1 K120 (216) (120-217), hinge 1-15 (218-
  2. Drug

    Rifampin

    go.drugbank.com/drugs/DB01045
    ApprovedInvestigational

    Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968. … [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).[A263768]

    Synonyms: 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV, 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetateMixtures: RIFAMPICINA 300 MG + ISONIAZIDA 150 MG, RIFAMPICINA 300 MG + ISONIAZIDA 150 MG
  3. Drug

    Beclomethasone dipropionate

    go.drugbank.com/drugs/DB00394
    ApprovedInvestigational

    Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and later in a dry powder inhaler and an aqueous nasal spray. … [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which acts on the glucocorticoid receptor to mediates its therapeutic action.

    Synonyms: (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 9-chloro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionateInternational brands: Clenil-A
  4. Drug

    Rexin G

    go.drugbank.com/drugs/DB16450
    Investigational

    Rexin-G is a tumor-targeted, injectable retroviral vector carrying a mutant form of the cyclin G1 gene. … It is under development by Epeius Biotechnologies for the potential treatment of metastatic cancer. It is also being investigated for preventing SARSCOV-2 viral entry.

    Synonyms: DeltaRex-G Retroviral Vector Encoding a Cyclin G1 Inhibitor, DeltaRex-GInternational brands: Rexin-G
  5. Drug

    alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14003
    Approved

    , males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males … The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months

    Synonyms: Vitamin E acetate, α-tocopherol acetateMixtures: Vitamin A (100,000 Iu) and Vitamin E (20 Iu) Oral Liquid Preparation, Vitamin E 400 I.U. & Selenium 50 Mcg Capsules
  6. Drug

    Cyclo(his-pro)

    go.drugbank.com/drugs/DB02414
    Experimental

    Synonyms: (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, cyclo(L-His-L-Pro)Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  7. Drug

    AD-214

    go.drugbank.com/drugs/DB18412
    Investigational

    Synonyms: Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and 3 of the Fc region of a mutated human IgG1
  8. Drug

    Pancrelipase

    go.drugbank.com/drugs/DB00085
    ApprovedInvestigational

    Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. … [L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.

    Mixtures: PANLIPAZ 170/80 MG ENTERİK KAPLI FİLM TABLET, 20 ADET, PANKREOFLAT 170/310 MG GRANÜL (22x2 g poşet)Products: FESTAL N 220 MG ENTERİK KAPLI TABLET, 100 ADET, FESTAL N 220 MG ENTERİK KAPLI TABLET, 20 ADET
  9. Drug

    Ipratropium

    go.drugbank.com/drugs/DB00332
    ApprovedInvestigational

    [A176939] It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. … Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent.

    Mixtures: PRALAS 100 MCG/20 MCG İNHALASYON İÇİN ÇÖZELTİ İÇEREN ÖLÇÜLÜ DOZLU AEROSOL, 1 ADET, İPRAVENT 20 MCG/100 MCG AEROSOL İNHALASYONU, SÜSPANSİYON (200 DOZ)Products: A-TROFINSA, ATROVENT 500 MG /2ML
  10. Drug

    Cephalexin

    go.drugbank.com/drugs/DB00567
    ApprovedInvestigationalVet approved

    [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. … [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971.

    Synonyms: (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acidInternational brands: L-Keflex