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Displaying results 791 - 800 of 8696 in total
  1. Drug

    Apixaban

    go.drugbank.com/drugs/DB06605
    ApprovedInvestigational

    Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Mar-apixaban
  2. Drug

    Mitoxantrone

    go.drugbank.com/drugs/DB01204
    ApprovedInvestigational

    An anthracenedione-derived antineoplastic agent.

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: MITOXANTRONE BAXTER SOLUTION FOR INJECTION 20MG/10ML (2MG/ML), Ebexantron 2 mg/ml - Konzentrat zur Herstellung einer Infusionslösung
  3. Drug

    Wheat

    go.drugbank.com/drugs/DB10579
    Approved

    Wheat allergenic extract is used in allergenic testing.

    Synonyms: Xiao mai
  4. Drug

    SAR-439459

    go.drugbank.com/drugs/DB17864
    Investigational

    SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody.[A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis Imperfecta.

    Synonyms: MAB HUMAN (IGG4) ANTI P01137 (TGFB1_HUMAN) OR ANTI P61812 (TFGB2_HUMAN) OR ANTI P10600 (TGFB3_HUMAN)(SAR439459)
  5. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.

    Mixtures: Lisnopril/hctz (type P), Lisnopril/hctz (type P)Categories: Antihypertensive Agents Indicated for Hypertension
  6. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    patients may require for surgery. … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery.

    Products: BRIDION 100MG/ML SOLUTION FOR INJECTION, Bridion Solution For Injection 100mg/ml
  7. Drug

    Nicardipine

    go.drugbank.com/drugs/DB00622
    ApprovedInvestigational

    A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the ...

    Categories: Antihypertensive Agents Indicated for Hypertension, Adrenergic alpha-1 Receptor AntagonistsProducts: Nicardiin 1mg/ml Solution for Infusion
  8. Drug

    PMC-403

    go.drugbank.com/drugs/DB18132
    Investigational

    PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.

    Synonyms: a fully human monoclonal antibody that binds and activates the Tie2 receptor
  9. Drug

    Dipyridamole

    go.drugbank.com/drugs/DB00975
    ApprovedInvestigational

    A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 199...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Dipyridamole for Injection
  10. Drug

    ALLO-715

    go.drugbank.com/drugs/DB18640
    Investigational

    ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen (BCMA).

    Synonyms: Allogenic Chimeric Antigen Receptor T Cells Targeting B Cell Maturation Antigen (BCMA)