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Antihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalPEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529]. … Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product _Adynovate_ [FDA label].
Categories: Amino Acids, Peptides, and ProteinsProducts: ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION, ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONNizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Categories: Alimentary Tract and Metabolism, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Synonyms: N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamineKetotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigational[A231204] Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. … available and indicated as an add-on therapy for children with atopic asthma.
Categories: Decongestants and AntiallergicsProducts: Up and Up Eye Itch Relief, Nu-ketotifen Syrup - 1mg/5mlLevofloxacin
go.drugbank.com/drugs/DB01137ApprovedInvestigational[A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.[A190663] … [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin[A190663] and remains stereochemically stable following administration
Categories: Alimentary Tract and Metabolism, levofloxacin and ornidazoleProducts: NEO LEVO, Levaquin 25mg/mlChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule cells in the kidney. … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment.
Mixtures: ATENOCOMP 1A 100MG/25MG, ATENOCOMP 1A 100MG/25MGCategories: chlortalidone and potassium, chlortalidone and potassium-sparing agentsCabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigational[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376] … [A7056, A260421, A260621] Cabazitaxel is used to treat metastatic castration-resistant prostate cancer. It was first approved by the FDA on June 17, 2010.
Categories: Antineoplastic and Immunomodulating AgentsProducts: JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION, Concentrate and Solvent for Solution for Infusion 60mg/1.5mlMeloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approvedMeloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. … Meloxicam is available in oral, transdermal, and intravenous formulations.
Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, bupivacaine and meloxicamProducts: Nu-meloxicam, BUTAZOLIDINA-NF 15 MG TABLETASGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A234364] This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects. … [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections including those caused by
Mixtures: Garasone Ophthalmic and Otic Solution, QUADRIDERM NFCategories: Ophthalmological and Otological PreparationsApixaban
go.drugbank.com/drugs/DB06605ApprovedInvestigationalApixaban was approved by the FDA on December 28, 2012[L6043]. … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic
Categories: Blood and Blood Forming OrgansProducts: Nb-apixaban, Nb-apixaban TabletTuroctocog alfa
go.drugbank.com/drugs/DB09109Approved[A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] … Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally
Categories: Amino Acids, Peptides, and ProteinsProducts: NovoEight 500IU Powder and Solvent for Solution for Injection, NovoEight 1000IU Powder and Solvent for Solution for Injection