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Oxmetidine
go.drugbank.com/drugs/DB21430ExperimentalOxmetidine is a small molecule drug. The usage of the INN stem '-tidine' in the name indicates that Oxmetidine is a histamine- H2-receptor antagonist, cimetidine derivative.
Tisolagiline
go.drugbank.com/drugs/DB21655ExperimentalTisolagiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Tisolagiline is a monoamine oxydase (MAO)-inhibitor type B.
Mosperafenib
go.drugbank.com/drugs/DB21673ExperimentalMosperafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Mosperafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.
QRX-411
go.drugbank.com/drugs/DB17868ExperimentalIt addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.
GSK2245035
go.drugbank.com/drugs/DB16076InvestigationalGSK2245035 is under investigation in clinical trial NCT02833974 (Effect of the GSK2245035 on the Allergen-induced Asthmatic Response).
Stapokibart
go.drugbank.com/drugs/DB18990InvestigationalStapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).
ST-36
go.drugbank.com/drugs/DB17275ExperimentalST-36 is a cell-penetrating dominant-negative form of activating transcription factor 5. In 2017, it received orphan drug designation by the FDA for the treatment of glioma.[L47341]
HMI-203
go.drugbank.com/drugs/DB18520InvestigationalHMI-203 is an investigational gene therapy developed by Homology Medicines, Inc. … It consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate-2-sulfatase (hIDS).
Sitravatinib
go.drugbank.com/drugs/DB15036InvestigationalSitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma).