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Gontivimab
go.drugbank.com/drugs/DB16179InvestigationalGontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus
IPI-549
go.drugbank.com/drugs/DB16296InvestigationalIPI-549 is under investigation in clinical trial NCT03795610 (Window of Opportunity Study of IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma).
Irsenontrine
go.drugbank.com/drugs/DB19044InvestigationalIrsenontrine is under investigation in clinical trial NCT03467152 (Study to Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia
Vezocolmitide
go.drugbank.com/drugs/DB21751InvestigationalVezocolmitide is under investigation in clinical trial NCT06178679 (Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease
Gam-COVID-Vac
go.drugbank.com/drugs/DB15848InvestigationalJune 2020, and were completed in early August 2020. … Gam-COVID-Vac was created by Gamaleya Research Institute of Epidemiology and MIcrobiology in Russia.
Tengonermin
go.drugbank.com/drugs/DB16689Investigational[A233270] A study also demonstrated that binding of the NGR-motif to CD13 determined both the homing of NGR-hTNF to tumor vessels and the increase in its antiangiogenic activity.[A233270]
Defoslimod
go.drugbank.com/drugs/DB20763InvestigationalDefoslimod is under investigation in clinical trial NCT01800812 (Effects of OM-174 in Adult Patients With Solid Tumors). Defoslimod has a monoisotopic molecular weight of 1148.65 Da. … The usage of the INN stem '-imod' in the name indicates that Defoslimod is a immunomodulator, both stimulant/suppressive and stimulant.
Empesertib
go.drugbank.com/drugs/DB19473InvestigationalEmpesertib is under investigation in clinical trial NCT02138812 (Phase I Dose Escalation of Oral BAY1161909 in Combination With Intravenous Paclitaxel). … The usage of the INN stem '-sertib' in the name indicates that Empesertib is a serine/threonine kinase inhibitor.
Ancremonam
go.drugbank.com/drugs/DB19710InvestigationalAncremonam is under investigation in clinical trial NCT03377426 (LYS228 PK, Clinical Response, Safety and Tolerability in Patients With Complicated Urinary Tract Infection (cUTI)). … The usage of the INN stem '-monam' in the name indicates that Ancremonam is a monobactam antibiotic.
Mevociclib
go.drugbank.com/drugs/DB21454InvestigationalMevociclib is under investigation in clinical trial NCT03134638 (A Study of SY-1365 in Adult Patients With Advanced Solid Tumors). Mevociclib has a monoisotopic molecular weight of 586.26 Da. … The usage of the INN stem '-ciclib' in the name indicates that Mevociclib is a cyclin dependant kinase inhibitor.