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Displaying results 8031 - 8040 of 10000 in total
  1. Drug

    Olokizumab

    go.drugbank.com/drugs/DB13127
    Investigational

    Targeting IL-6 function can be achieved directly, or through interrupting the IL-6 receptor or gp130 receptor axes. … Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system.

  2. Drug

    MDX-1379

    go.drugbank.com/drugs/DB05329
    Investigational

    MDX-1379 vaccine consists of two gp100 melanoma peptides. This drug is underinvestigation to treat malignant melanoma.

  3. Drug

    Aluminum chlorohydrex propylene glycol

    go.drugbank.com/drugs/DB11208
    Approved

    Aluminum chlorohydrex propylene glycol is a complex consisting of Aluminum Chorohydrate and propylene glycol (PG). … It is an antiperspirant active ingredient found in antiperspirant drug products for over-the-counter human use.

  4. Drug

    AP5346

    go.drugbank.com/drugs/DB04992
    Investigational

    AP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer. It is being pursued by Access Pharmaceuticals, Inc.

  5. Drug

    3,4-Methylenedioxy-N-isopropylamphetamine

    go.drugbank.com/drugs/DB06112
    Experimental

    MDI-P is also a potential therapeutic agent for the treatment of the symptoms of cystic fibrosis ("CF"). … MDI-P has been shown to be effective in killing HIV in cell culture. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).

    Synonyms: 3,4-Methylenedioxy-N-isopropylamphetamine
  6. Drug

    DOTMP HO-166

    go.drugbank.com/drugs/DB05380
    Experimental

    SRT is designed to be used in combination with high-dose chemotherapy producing a direct therapeutic effect on the tumor sites in the bone plus a general bone-marrow effect to destroy myeloma cells in … DOTMP HO-166 is used in skeletal targeted radiotherapy (STR).

  7. Drug

    Elsulfavirine

    go.drugbank.com/drugs/DB14929
    Investigational

    Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food

    Categories: Non-Nucleoside Reverse Transcriptase Inhibitors
  8. Drug

    Amcipatricin

    go.drugbank.com/drugs/DB12333
    Investigational

    SPK-843 exhibits dose-dependent efficacy on murine pulmonary aspergillosis models. … Amcipatricin has been used in trials studying the treatment of Cryptococcosis or Aspergillosis Infections.

  9. Drug

    Pazufloxacin

    go.drugbank.com/drugs/DB11774
    Investigational

    Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).

    Categories: Drugs for Treatment of Tuberculosis
  10. Drug

    rhIGFBP-3

    go.drugbank.com/drugs/DB05897
    Investigational

    of human. … It is developed by Insmed and is currently under phase I of the clinical trial.