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NTx-265
go.drugbank.com/drugs/DB05649InvestigationalNTx-265 is a combination of two currently marketed large molecules designed to stimulate the growth and differentiation of neural stem cells in adults who have suffered a stroke – the second leading cause … It is also investigating use of the compound for neurodegenerative disorders, such as Huntington’s disease and Alzheimer’s disease.
Paraoxon
go.drugbank.com/drugs/DB13495ExperimentalCategories: Antiglaucoma Preparations and Miotics, Compounds used in a research, industrial, or household settingSonedenoson
go.drugbank.com/drugs/DB12443InvestigationalSonedenoson has been used in trials studying the treatment of Foot Ulcer, Diabetic and Diabetes Complications.
Categories: Nucleic Acids, Nucleotides, and NucleosidesAZD-8965
go.drugbank.com/drugs/DB32868ExperimentalAZD-8965 is a small molecule inhibitor of ARG-1 and ARG-2.
Tiragolumab
go.drugbank.com/drugs/DB16409InvestigationalTiragolumab is under investigation in clinical trial NCT04513925 (A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-small
Categories: Amino Acids, Peptides, and ProteinsAllovectin-7
go.drugbank.com/drugs/DB17439InvestigationalAllovectin-7 or allovectin-7(r) is a lipid complex that contains the DNA sequences encoding HLA-B7 and beta-2 microglobulin. … It was discontinued after it failed to improve the objective response rate or overall survival versus first-line chemotherapy in malignant melanoma.[A255207]
Categories: Nucleic Acids, Nucleotides, and NucleosidesBudigalimab
go.drugbank.com/drugs/DB16668InvestigationalBudigalimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination … With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
Categories: Amino Acids, Peptides, and ProteinsOntamalimab
go.drugbank.com/drugs/DB15298InvestigationalOntamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Categories: Amino Acids, Peptides, and ProteinsAmdoxovir
go.drugbank.com/drugs/DB06619InvestigationalCategories: Nucleic Acids, Nucleotides, and NucleosidesElezanumab
go.drugbank.com/drugs/DB15240InvestigationalElezanumab is under investigation in clinical trial NCT03737812 (A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis).
Categories: Amino Acids, Peptides, and Proteins