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Pentamustine
go.drugbank.com/drugs/DB21291ExperimentalPentamustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Pentamustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative.
Izilendustat
go.drugbank.com/drugs/DB21532ExperimentalIzilendustat is a small molecule drug. The usage of the INN stem '-dustat' in the name indicates that Izilendustat is a hypoxia inducible factor (HIF) prolyl hydroxylase inhibitor.
Civorebrutinib
go.drugbank.com/drugs/DB21641ExperimentalCivorebrutinib is a small molecule drug. The usage of the INN stem '-brutinib' in the name indicates that Civorebrutinib is a agammaglobulinaemia tyrosine kinase (Bruton tyrosine kinase) inhibitor.
RO7830698
go.drugbank.com/drugs/DB33974ExperimentalRO7830698 is a biologic drug. RO7830698 is under investigation in clinical trial NCT07822334 (A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease).
Tasurgratinib
go.drugbank.com/drugs/DB21222InvestigationalTasurgratinib is a small molecule drug. The usage of the INN stem '-gratinib' in the name indicates that Tasurgratinib is a fibroblast growth factor receptor (FGFR) inhibitor. … Tasurgratinib is under investigation in clinical trial NCT04962867 (NCCH2006/MK010 Trial (FORTUNE Trial)). Tasurgratinib has a monoisotopic molecular weight of 587.27 Da.
Tersolisib
go.drugbank.com/drugs/DB21752InvestigationalSTX-478 is under investigation in clinical trail NCT05768139 (First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Hycanthone
go.drugbank.com/drugs/DB14061ExperimentalPotentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
siG12D LODER
go.drugbank.com/drugs/DB16329InvestigationalsiG12D LODER is under investigation in clinical trial NCT01676259 (A Phase 2 Study of Sig12d LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer).
Vorbipiprant
go.drugbank.com/drugs/DB16111InvestigationalCR6086 is under investigation in clinical trial NCT03163966 (A Study of the EP4 Antagonist CR6086 in Combination With Methotrexate, in Dmard-naïve Patients With Early Rheumatoid Arthritis).