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ASP-8731
go.drugbank.com/drugs/DB17696InvestigationalDeveloped by Mitobridge, it is being investigated for the treatment of sickle cell disease.[L46093]
Otamixaban
go.drugbank.com/drugs/DB06635InvestigationalIt is currently being developed by the French pharmaceutical company Sanofi-Aventis as a treatment for acute coronary syndrome.
PF-03882845
go.drugbank.com/drugs/DB11814InvestigationalPF-03882845 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 and Type 2 Diabetic Nephropathy.
BMS-830216
go.drugbank.com/drugs/DB14787InvestigationalBMS-830216 is under investigation in clinical trial NCT00909766 (Safety, Pharmacokinetics and Pharmacodynamics Study to Evaluate BMS-830216 in Obese Subjects).
Lucerastat
go.drugbank.com/drugs/DB14872InvestigationalLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
OPB-111077
go.drugbank.com/drugs/DB16630InvestigationalOPB-111077 is a novel inhibitor of STAT3 and mitochondrial oxidative phosphorylation. It has demonstrated promising anticancer activity in preclinical models.
JZP-386 free base
go.drugbank.com/drugs/DB17068ExperimentalIts safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.
Emprumapimod
go.drugbank.com/drugs/DB17603InvestigationalEmprumapimod is a potent, orally active and selective inhibitor of p38α mitogen-activated kinase inhibitor. It was investigated for dilated cardiomyopathy.
Befotertinib
go.drugbank.com/drugs/DB18844InvestigationalBefotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive Patients With Advanced Egfr-mutant Lung Cancer).