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Displaying results 8081 - 8090 of 10000 in total
  1. Drug

    Chloropyramine

    go.drugbank.com/drugs/DB08800
    Investigational

    Chlorpyramine is a first generation antihistamine used in Eastern European countries to treat bronchial asthma as well as allergice rhinitis, allergic conjunctivitis, and other allergic reactions.

  2. Drug

    Sampatrilat

    go.drugbank.com/drugs/DB21283
    Experimental

    Sampatrilat is a small molecule drug. Sampatrilat has a monoisotopic molecular weight of 584.25 Da.

    Categories: Agents Acting on the Renin-Angiotensin System
  3. Drug

    IMM-101

    go.drugbank.com/drugs/DB15850
    Investigational

    As of July 2020, researchers from the Ottawa Hospital and Queen’s University, in partnership with the Canadian Cancer Society-funded Canadian Cancer Trials Group (CCTG), are conducting a trial in over … 1500 participants to evaluate the vaccine’s protective effects on cancer patients from severe COVID-19 infection (NCT04442048).

    Categories: Complex Mixtures
  4. Target

    Cyclin-dependent kinases

    go.drugbank.com/bio_entities/BE0010231
    TargetHumans

    Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex … This complex is inactive when in the 7SK snRNP complex form (PubMed:10574912, PubMed:10757782, PubMed:11145967, PubMed:11575923, PubMed:11809800, PubMed:11884399, PubMed:14701750, PubMed:16109376, PubMed

    Synonyms: Mediator complex subunit CDK8, Tat-associated kinase complex catalytic subunit
  5. Drug

    Piperacetazine

    go.drugbank.com/drugs/DB06808
    ApprovedVet approvedWithdrawn

    Piperacetazine was an antipsychotic.

  6. Drug

    Vevorisertib

    go.drugbank.com/drugs/DB21481
    Investigational

    Vevorisertib is under investigation in clinical trial NCT02761694 (Vevorisertib (ARQ 751) as a Single Agent or in Combination With Other Anti-Cancer Agents, in Solid Tumors With PIK3CA / AKT / PTEN Mutations … The usage of the INN stem '-sertib' in the name indicates that Vevorisertib is a serine/threonine kinase inhibitor.

  7. Drug

    Gam-COVID-Vac

    go.drugbank.com/drugs/DB15848
    Investigational

    June 2020, and were completed in early August 2020. … Gam-COVID-Vac was created by Gamaleya Research Institute of Epidemiology and MIcrobiology in Russia.

  8. Drug

    Fulzerasib

    go.drugbank.com/drugs/DB21609
    Investigational

    Fulzerasib is under investigation in clinical trial NCT06936644 (A Multicenter, Single-arm Phase II Study to Evaluate the Efficacy and Safety of Fulzerasib (IBI351) in Combination With Ivonescimab (AK- … The usage of the INN stem '-rasib' in the name indicates that Fulzerasib is a Ras protein inhibitor.

  9. Drug

    Amcipatricin

    go.drugbank.com/drugs/DB12333
    Investigational

    In preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp. … Amcipatricin has been used in trials studying the treatment of Cryptococcosis or Aspergillosis Infections.

  10. Drug

    5-methoxy-N,N-dimethyltryptamine

    go.drugbank.com/drugs/DB14010
    IllicitInvestigational

    This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South America in religious and spiritual rituals. … It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad.

    Categories: N,N-DimethyltryptamineSynonyms: 5-methoxy-N,N-dimethyltryptamine, N,N-dimethyl-5-methoxytryptamine