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Displaying results 801 - 810 of 10000 in total
  1. Drug

    Mycophenolic acid

    go.drugbank.com/drugs/DB01024
    ApprovedInvestigational

    Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. … Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis.

    Categories: Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
  2. Drug

    Halicin

    go.drugbank.com/drugs/DB15624
    Experimental

    Synonyms: 2-amino-5-[(5-nitro-2-thiazolyl)thio]-1,3,4-thiadiazoleCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Furaltadone

    go.drugbank.com/drugs/DB16567
    Investigational

    Synonyms: (±)-5-(MORPHOLINOMETHYL)-3-((5-NITROFURFURYLIDENE)AMINO)-2-OXAZOLIDINONECategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Brensocatib

    go.drugbank.com/drugs/DB15638
    Approved

    [A274348] Brensocatib is a first-in-class dipeptidyl peptidase 1 (DPP1) inhibitor that inhibits neutrophil serine proteases, addressing a key driver of this inflammation. … [A274348] Brensocatib was approved by the US FDA on August 12, 2025, for use in adults and pediatric patients with NCFB.[L53808,L53813]

    Categories: MATE 1 Inhibitors, MATE 2 InhibitorsSynonyms: (S)-N-((S)-1-Cyano-2-(4-(3-methyl-2-oxo-2,3-dihydrobenzo-(d)oxazol-5-yl)phenyl)ethyl)-1,4-oxazepane-2-carboxamide
  5. Drug

    Bupicomide

    go.drugbank.com/drugs/DB19556
    Experimental

    Bupicomide is a small molecule drug. Bupicomide has a monoisotopic molecular weight of 178.11 Da.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-butylpicolinamide
  6. Drug

    Sulfabromomethazine

    go.drugbank.com/drugs/DB11547
    ExperimentalVet approved

    Synonyms: 5-bromosulfamethazine
  7. Drug

    Furazolidone

    go.drugbank.com/drugs/DB00614
    InvestigationalVet approved

    A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase.

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone, 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine
  8. Drug

    2-(5-fluoro-pentyl)-2-methyl-malonic-acid

    go.drugbank.com/drugs/DB16029
    Investigational

    2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).

    Synonyms: 2-(5-fluoro-pentyl)-2-methyl-malonic-acid
  9. Drug

    Chlorthalidone

    go.drugbank.com/drugs/DB00310
    ApprovedInvestigational

    [A173863] In particular, the ALLHAT trial confirmed the role of thiazide diuretics as first-line therapy and demonstrated that chlorthalidone had a statistically significant lower incidence of stroke and … [A176324] Chlorthalidone is considered first-line therapy for management of uncomplicated hypertension as there is strong evidence from meta-analyses that thiazide diuretics such as chlorthalidone reduce

    Mixtures: TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADET, TENORETIC 100 MG/25 MG FILM TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Disperse Blue 106

    go.drugbank.com/drugs/DB14203
    Approved

    Disperse Blue 106 is used in allergenic testing.

    Synonyms: 5-Nitro-2-(2-methyl-4-(N-ethyl-N-(2-hydroxyethyl)amino)phenylazo)thiazole