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Abivertinib
go.drugbank.com/drugs/DB15327InvestigationalThe study is expected to be completed in March 2021.[L17398] … [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies.
CoVac-1
go.drugbank.com/drugs/DB16429InvestigationalIt is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults (pVAC))[L30428] and aims to induce broad … Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein[A226588].
Elsubrutinib
go.drugbank.com/drugs/DB18850InvestigationalElsubrutinib is under investigation in clinical trial NCT04451772 (A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants … With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State).
Hu-rhEGF-rP64k/Mont
go.drugbank.com/drugs/DB15781InvestigationalHu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated
Escin
go.drugbank.com/drugs/DB15907Investigationalprognosis in massive cerebral infarction) and NCT05263167 (aimed at reducing edema after intracerebral hemorrhage). … Sodium aescinate is under investigation in clinical trials for its potential to treat cerebral conditions, including NCT04247659 (studying the relationship between asymmetric vascular sign of cortex and
BBM-H803
go.drugbank.com/drugs/DB17700InvestigationalIt consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene.
Upleganan
go.drugbank.com/drugs/DB21618InvestigationalUpleganan is under investigation in clinical trial NCT04865393 (Phase 1 Study of PK and Safety of SPR206 in Subjects With Various Degrees Of Renal Function).
Atigliflozin
go.drugbank.com/drugs/DB21394InvestigationalAtigliflozin is under investigation in clinical trial NCT00361738 (Dose-Ranging Study Evaluating AVE2268 in Patients With Type 2 Diabetes Not Adequately Controlled by a Metformin Treatment).
Dazdotuftide
go.drugbank.com/drugs/DB21550InvestigationalDazdotuftide is under investigation in clinical trial NCT05042609 (A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma).
Muvalaplin
go.drugbank.com/drugs/DB21568InvestigationalMuvalaplin is under investigation in clinical trial NCT05563246 (A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events).