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Dabocemagene autoficel
go.drugbank.com/drugs/DB17878InvestigationalDabocemagene autoficel is an _ex vivo_, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. … Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.[L46797]
Lanabecestat
go.drugbank.com/drugs/DB14814InvestigationalLanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).
KRN-5500
go.drugbank.com/drugs/DB15215InvestigationalKRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).
Oplunofusp
go.drugbank.com/drugs/DB15313InvestigationalDAS-181 is under investigation in clinical trial NCT00527865 (Single Dose Escalating Study of DAS181 in Adults).
Apratastat
go.drugbank.com/drugs/DB13020InvestigationalTmi 005 is under investigation in clinical trial NCT00095342 (Study Evaluating TMI-005 in Active Rheumatoid Arthritis).
BP-14979
go.drugbank.com/drugs/DB16302InvestigationalBP-14979 is under investigation in clinical trial NCT01785147 (Efficacy and Safety of BP1.4979 in Smoking Cessation).
Arpraziquantel
go.drugbank.com/drugs/DB11749Investigational(R)-Praziquantel is under investigation in clinical trial NCT02271984 (Relative Bioavailability Trial of L-Praziquantel in Healthy Volunteers).
Enoblituzumab
go.drugbank.com/drugs/DB15017InvestigationalEnoblituzumab is under investigation in clinical trial NCT02982941 (Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors).
Pittsburgh Compound B
go.drugbank.com/drugs/DB15161InvestigationalPittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD).
Synonyms: (N-methyl-(11C))2-(4'-methylaminophenyl)-6-hydroxybenzothiazoleMAX-40279
go.drugbank.com/drugs/DB15191InvestigationalMAX-40279 is under investigation in clinical trial NCT03412292 (MAX-40279 in Subjects With Acute Myelogenous Leukemia (AML)).
Synonyms: 7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno (3,2-d)pyrimidin-2-amine