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GSK2245035
go.drugbank.com/drugs/DB16076InvestigationalGSK2245035 is under investigation in clinical trial NCT02833974 (Effect of the GSK2245035 on the Allergen-induced Asthmatic Response).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingStapokibart
go.drugbank.com/drugs/DB18990InvestigationalStapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).
Synonyms: Immunoglobulin G4 [227-proline], anti-(human interleukin 4 receptor subunit α) (human-Mus musculus monoclonal CM310 γ4-chain), disulfide with human-Mus musculus monoclonal CM310 κ-chain, dimerEnrofloxacin
go.drugbank.com/drugs/DB11404InvestigationalVet approvedDue to the identification of fluoroquinolone-resistant strains of _Campylobacter_, in September 2005, the FDA withdrew the approval of enrofloxacin for its use in water to treat flocks of poultry. … Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use.
Categories: 4-Quinolones, P-glycoprotein substratesTalsupram
go.drugbank.com/drugs/DB09191ExperimentalTalsupram is a selective norepinephrine reuptake inhibitor (NRI). It was under research for the treatment of depression in 1960 and 1970 but it was never marketed. … Talsupram presents a similar structure to [citalopram].
Categories: Heterocyclic Compounds, 1-RingPizuglanstat
go.drugbank.com/drugs/DB19483ExperimentalPizuglanstat is a small molecule drug. The usage of the INN stem '-glanstat' in the name indicates that Pizuglanstat is a prostaglandin synthase inhibitor. … Pizuglanstat has a monoisotopic molecular weight of 508.28 Da.
Afacifenacin
go.drugbank.com/drugs/DB21385ExperimentalAfacifenacin is a small molecule drug. The usage of the INN stem '-fenacin' in the name indicates that Afacifenacin is a muscarinic receptor antagonist. … Afacifenacin has a monoisotopic molecular weight of 481.2 Da.
Fosifidancitinib
go.drugbank.com/drugs/DB21462ExperimentalFosifidancitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Fosifidancitinib is a Janus kinase inhibitor. … Fosifidancitinib has a monoisotopic molecular weight of 505.12 Da.
Gemnelatinib
go.drugbank.com/drugs/DB21513ExperimentalGemnelatinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Gemnelatinib is a tyrosine kinase inhibitor. … Gemnelatinib has a monoisotopic molecular weight of 524.23 Da.
Girocitinib
go.drugbank.com/drugs/DB21692ExperimentalGirocitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Girocitinib is a Janus kinase inhibitor. … Girocitinib has a monoisotopic molecular weight of 326.14 Da.
Nedemelteon
go.drugbank.com/drugs/DB21700ExperimentalNedemelteon is a small molecule drug. The usage of the INN stem '-melteon' in the name indicates that Nedemelteon is a melatonin receptor agonist. … Nedemelteon has a monoisotopic molecular weight of 258.14 Da.