Afacifenacin

DB21385ExperimentalSmall molecule

Afacifenacin is a small molecule drug. The usage of the INN stem '-fenacin' in the name indicates that Afacifenacin is a muscarinic receptor antagonist. Afacifenacin has a monoisotopic molecular weight...

Mechanism: Pharmacologically active on Sodium channel protein type 10 subunit alpha, Sodium channel protein type 11 subunit alpha, and Muscarinic acetylcholine receptor
Curator reviewed
Formula / weight: C₂₇H₂₆F₃N₃O₂ · 481.519 g/mol (avg)
Code names: NS-986

Resolves to

Compound

UNIIXQU62QZ74PCAS877606-63-8

Structure

InChIKeyIJUMFEAYOMCXAQ-VWLOTQADSA-NSMILESFC(F)(F)OC1=CC(CN2CCC(CC2)N2[C@@H](C3=CC=CC=C3)C3=CC=CC=C3NC2=O)=CC=C1

Targets

Q9Y5Y9SCN10AQ9UI33SCN11A

What you can answer from here — as of August 31, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with Afacifenacin, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account