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TMC-310911
go.drugbank.com/drugs/DB15623Investigational[L12045] It is being investigated for use in HIV-1 infections. … [L12045,A191643] TMC-310911 is currently being investigated, in combination with other HIV therapies and antivirals, as a potential treatment for COVID-19 caused by SARS-CoV-2.[L12012]
Amcasertib
go.drugbank.com/drugs/DB14866InvestigationalAmcasertib is under investigation in clinical trial NCT02483247 (A Study of BBI503 in Combination With Selected Anti-Cancer Therapeutics in Adult Patients With Advanced Cancer).
APG-1387
go.drugbank.com/drugs/DB16095InvestigationalAPG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B).
L-deprenyl-D2 C-11
go.drugbank.com/drugs/DB12650ExperimentalL-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).
CHIR-124
go.drugbank.com/drugs/DB06852ExperimentalCHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.
Tretazicar
go.drugbank.com/drugs/DB04253InvestigationalTretazicar is under investigation in clinical trial NCT00746590 (Study of Anti-tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma).
BMS-830216
go.drugbank.com/drugs/DB14787InvestigationalBMS-830216 is under investigation in clinical trial NCT00909766 (Safety, Pharmacokinetics and Pharmacodynamics Study to Evaluate BMS-830216 in Obese Subjects).
Cobitolimod
go.drugbank.com/drugs/DB14819InvestigationalCobitolimod is under investigation in clinical trial NCT03178669 (The Efficacy of Cobitolimod in Patients With Moderate to Severe Active Ulcerative Colitis).
Bimiralisib
go.drugbank.com/drugs/DB14846InvestigationalBimiralisib is under investigation in clinical trial NCT02723877 (PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)).
Lucerastat
go.drugbank.com/drugs/DB14872InvestigationalLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).