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Displaying results 811 - 820 of 8171 in total
  1. Drug

    Phentermine

    go.drugbank.com/drugs/DB00191
    ApprovedIllicitInvestigational

    [A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. … Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Adipex-P
  2. Drug

    Glycyrrhizic acid

    go.drugbank.com/drugs/DB13751
    ApprovedInvestigational

    When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium glycyrrhizin. … [A33062] From January 2014, glycyrrhizic acid as part of the licorice extract was approved by the FDA as an existing food sweetener.

  3. Drug

    Synthetic Conjugated Estrogens, A

    go.drugbank.com/drugs/DB09317
    Approved

    However, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Metaraminol

    go.drugbank.com/drugs/DB00610
    Approved

    An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of norepinephrine.

  5. Drug

    Heparin

    go.drugbank.com/drugs/DB01109
    ApprovedInvestigational

    Furthermore, the effects of UH can typically be reversed by using protamine sulfate. … Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da.

    Mixtures: BARICUS 50 IU/%1/%10 JEL , 50 G, HEPARINISED SALINE INJECTION 10 iu/mlProducts: Hep-Lock U/P, THROMBAREDUCT SAN 30000IE
  6. Drug

    PI-0824

    go.drugbank.com/drugs/DB05516
    Investigational

    Pemphigus vulgaris (PV) is an autoimmune disease affecting approximately 40,000 people worldwide. … People with PV produce antibodies that attack the cells of the skin, resulting in blisters which, if left untreated, can lead to devastating infections and discomfort.

  7. Drug

    Pentazocine

    go.drugbank.com/drugs/DB00652
    ApprovedVet approved

    It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)

    Categories: P-glycoprotein substratesInternational brands: Talwin PX
  8. Drug

    PX-478

    go.drugbank.com/drugs/DB06082
    Investigational

    PX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express HIF-1 alpha. … PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma.

  9. Drug

    Opium

    go.drugbank.com/drugs/DB11130
    ApprovedIllicit

    This plant is an integrant of the Papaveraceae family, and it is characterized by solitary leaves and capsulated fruits.

    Mixtures: Donnagel-PG Liq, Donnagel-PG CapCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Streptomycin

    go.drugbank.com/drugs/DB01082
    ApprovedInvestigationalVet approved

    Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s. … [A233325,A232294] Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now primarily used as