Pentazocine

DB00652ApprovedVet approvedSmall moleculeOpiate Partial AgonistsPartial Opioid Agonist/Antagonist

Pentazocine is an analgesic used to treat moderate to severe pain. The first mixed agonist-antagonist analgesic to be marketed.

Chemical structure of Pentazocine
Mechanism
Curator reviewed
Primary indication
For the relief of moderate to severe pain.Curator reviewed · 7 structured indications
Formula / weight
C19H27NO · 285.431 g/mol (avg)
First approval
Canada, 2000 · United States, 1982
Code names
CS 350 · NIH 7958 · Win 20228

Resolves to

Compound
UNIIRP4A60D26LCAS359-83-1ChEMBLCHEMBL100116ChEBI182080PubChem4736KEGGD00498
Clinical / RWD
RxNorm8001ATCN02AD01ATCN02AD51PharmGKBPA164744326
Structure
InChIKeyVOKSWYLNZZRQPF-UHFFFAOYSA-NSMILESCC1C2CC3=C(C=C(O)C=C3)C1(C)CCN2CC=C(C)C
Targets
Q99720SIGMAR1P35372OPRM1P41145OPRK1
Transporters
P08183ABCB1

What you can answer from here — as of September 25, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
927Drug interactionsStructured to mechanism, not free text
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10Clinical trialsPhase, status and sponsor resolved per trial
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7Structured indicationsCondition, population, route and combination as fields, not prose
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21ContraindicationsEach with its own population and attribute set
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42Marketed productsAcross 4 countries and 24 labellers
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2ATC codesIncluding every combination product, plus 23 drug categories
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15+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Pentazocine, and which of those have an active Phase 3 trial?

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