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Thienylfentanyl
go.drugbank.com/drugs/DB09180ExperimentalIllicitThienylfentanyl is a fentanyl analog analgesic that was sold on the black market in the 1980s until the Federal Analog Act scheduled drugs based on structural similarity rather than scheduling drugs individually … Thienylfentanyl has a similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide.
ARG098
go.drugbank.com/drugs/DB06338ExperimentalARG098 (anti-Fas IgM monoclonal antibody) was studied in a Phase I clinical trial in 2007 involving patients with rheumatoid arthritis.
WNY0824
go.drugbank.com/drugs/DB23606Experimental[A274253] It is a dual inhibitor of PLK-1 and BRET-4, which have both been found to be involved in CRPC via suppression of AR/MYC-mediated transcription. [A274258]
Tigatuzumab
go.drugbank.com/drugs/DB15101InvestigationalTigatuzumab is under investigation in clinical trial NCT00991796 (CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)).
Categories: Amino Acids, Peptides, and ProteinsND7001
go.drugbank.com/drugs/DB05142ExperimentalKnown drug targets of ND7001 including phosphodiesterase 2A, cGMP-stimulated and cGMP-dependent 3',5'-cyclic phosphodiesterase. It is a new type of antidepressant drug with anxiolytic activity.
Aminomethylbenzoic acid
go.drugbank.com/drugs/DB13244ExperimentalAminomethylbenzoic acid may be useful as an antifibrinolytic agent [A174994].
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsMK-8189
go.drugbank.com/drugs/DB19153InvestigationalMK-8189 is under investigation in clinical trial NCT04624243 (Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)).
Synonyms: 4-PYRIMIDINAMINE, 2-METHYL-6-(((1S,2S)-2-(5-METHYL-2-PYRIDINYL)CYCLOPROPYL)METHOXY)-N-((5-METHYL-1,3,4-THIADIAZOL-2-YL)METHYL)-Drisapersen
go.drugbank.com/drugs/DB13688ApprovedWithdrawnCategories: Nucleic Acids, Nucleotides, and NucleosidesCorynebacterium diphtheriae CRM197 protein
go.drugbank.com/drugs/DB16712ApprovedInvestigationalCategories: Amino Acids, Peptides, and ProteinsSonepcizumab
go.drugbank.com/drugs/DB06305InvestigationalA humanized monoclonal antibody directed against sphingosine 1-phosphate (S1P) with potential antiangiogenic and antineoplastic activities.
Categories: Amino Acids, Peptides, and Proteins