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Displaying results 8271 - 8280 of 10000 in total
  1. Drug

    AMB-301

    go.drugbank.com/drugs/DB18094
    Experimental

    AMB-301 is an AAV gene therapy delivering E-selectin.[L48101] It is under investigation for the treatment of Buerger disease.

  2. Drug

    HRS-1167

    go.drugbank.com/drugs/DB18703
    Investigational

    HRS-1167 is under investigation in clinical trial NCT05473624 (Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors).

  3. Drug

    Roledumab

    go.drugbank.com/drugs/DB16317
    Investigational

    Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens rhd(rhesus blood group d antigen, rhd, cd240d)), homo sapiens monoclonal antibody
  4. Drug

    CTB001

    go.drugbank.com/drugs/DB18316
    Investigational

    CTB001 is an anti-claudin 18.2 autologous chimeric antigen receptor (CAR) T-cell therapy under investigation for the treatment of gastric cancers.[L48146]

  5. Drug

    Nisoxetine

    go.drugbank.com/drugs/DB09186
    Experimental

    It was originally investigated as an antidepressant but has no current clinical applications aside from being a research standard SNRI. … Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s.

  6. Drug

    Adrafinil

    go.drugbank.com/drugs/DB08925
    ApprovedWithdrawn

    It is also been used off-label to prevent fatigue or falling asleep for extended periods of time. Adrafinil does not currently have FDA approval and is thus unregulated in the United States. … Adrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients.

  7. Drug

    Gevokizumab

    go.drugbank.com/drugs/DB12119
    Investigational

    Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.

  8. Drug

    alpha-Conotoxin VC 1.1

    go.drugbank.com/drugs/DB05724
    Experimental

  9. Drug

    Tuparstobart

    go.drugbank.com/drugs/DB19118
    Investigational

    Tuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS … ≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and Neck).

    Synonyms: Immunoglobulin G1 [301-alanine,de-C-terminal-lysine], anti-(human lymphocyte activation gene-3 protein) (human-Mus musculus monoclonal INCAGN02385 γ1-chain), disulfide with human-Mus musculus monoclonal
  10. Drug

    Glucose-6-Phosphate

    go.drugbank.com/drugs/DB03581
    Experimental

    An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. … It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)