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CVN-424
go.drugbank.com/drugs/DB18958InvestigationalCVN-424 is under investigation in clinical trial NCT06006247 (Early Parkinson's Disease Monotherapy With CVN424).
Duvoglustat
go.drugbank.com/drugs/DB03206InvestigationalAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Deoxyribonuclease I
go.drugbank.com/drugs/DB16523InvestigationalCurrently, DNase I is being investigated against respiratory failure in COVID-19 in the clinical trial NCT04541979 (Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19). … It is normally found in saliva, urine, pancreatic secretions, and blood[A227723].
Flizasertib
go.drugbank.com/drugs/DB21613InvestigationalFlizasertib is under investigation in clinical trial NCT06602453 (A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse … The usage of the INN stem '-sertib' in the name indicates that Flizasertib is a serine/threonine kinase inhibitor.
Tizaterkib
go.drugbank.com/drugs/DB21296InvestigationalTizaterkib is under investigation in clinical trial NCT04305249 (Safety and Preliminary Efficacy of ATG-017 Monotherapy or Combination Therapy With Nivolumab in Advanced Solid Tumors and Hematological … The usage of the INN stem '-terkib' in the name indicates that Tizaterkib is a extracellular signal-regulated kinase (ERK) inhibitor.
Nisevokitug
go.drugbank.com/drugs/DB17561Investigationaland Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients). … Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety
Arlocabtagene autoleucel
go.drugbank.com/drugs/DB24024InvestigationalArlocabtagene Autoleucel is under investigation in clinical trial NCT06297226 (Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or
IL21120033
go.drugbank.com/drugs/DB32508ExperimentalIL21120033 is a first-in-class, small-molecule selective CXCR7 agonist.
α-Methylfentanyl
go.drugbank.com/drugs/DB01557ExperimentalIllicitα-Methylfentanyl is an analog of fentanyl with opioid analgesic properties.
Roluperidone
go.drugbank.com/drugs/DB13080InvestigationalRoluperidone has been used in trials studying the treatment of Schizophrenia.