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Displaying results 8281 - 8290 of 10000 in total
  1. Drug

    Perospirone

    go.drugbank.com/drugs/DB08922
    Investigational

    It is commonly present as the hydrated hydrochloride salt form. … It is also shown to be less associated with extrapyramidal symptoms as a side effect compared to [DB00502].

    Synonyms: SM-9018, cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximideCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  2. Drug

    Amfecloral

    go.drugbank.com/drugs/DB08924
    Experimental

    It acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and related compounds, except that the N-substituent, in this case, yields a compound that is active … Amfecloral is a stimulant drug of the phenethylamine and amphetamine chemical classes.

  3. Drug

    Adrafinil

    go.drugbank.com/drugs/DB08925
    ApprovedWithdrawn

    Adrafinil is metabolized to [modafinil]. … Adrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients.

  4. Drug

    Arsthinol

    go.drugbank.com/drugs/DB08928
    Experimental

    Considered well tolerated when compared to other related trivalent organoarsenicals, arsthinol has even undergone recent studies as a potential anticancer agent. … Arsthinol (INN) is an antiprotozoal agent that was first synthesized by Ernst A.H. Friedheim in 1949 via the complexing of acetarsol with 2,3-dimercaptopropanol.

  5. Drug

    Riociguat

    go.drugbank.com/drugs/DB08931
    ApprovedInvestigational

    Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for … Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. Treatment with riociguat costs USD $7,500 for 30 days of treatment.

    Synonyms: Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminateCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  6. Drug

    Macitentan

    go.drugbank.com/drugs/DB08932
    ApprovedInvestigational

    Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.

    Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  7. Drug

    Letosteine

    go.drugbank.com/drugs/DB08939
    Experimental

    Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.

  8. Drug

    Kebuzone

    go.drugbank.com/drugs/DB08940
    Investigational

    Kebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.

    Mixtures: Rheumesser 3 ml - AmpullenCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-Ring
  9. Drug

    Indoprofen

    go.drugbank.com/drugs/DB08951
    ApprovedWithdrawn

    A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-Ring
  10. Drug

    Ibuproxam

    go.drugbank.com/drugs/DB08955
    ApprovedWithdrawn

    Ibuproxam is a non steroidal anti-inflammatory drug (NSAID).

    Synonyms: p-Isobutylhydratropohydroxamic acidCategories: Non COX-2 selective NSAIDS