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Certoparin
go.drugbank.com/drugs/DB09261ApprovedCertoparin is part of the heparins of low molecular weight that presents high activity against the coagulation factor Xa. It is normally used to prevent deep venous thrombosis.
Imidafenacin
go.drugbank.com/drugs/DB09262InvestigationalIt is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical. … Imidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTechnetium Tc-99m tilmanocept
go.drugbank.com/drugs/DB09266ApprovedDetecting sentinel lymph node (SLN) is clinically useful in the prognosis and management of the disease, as it is considered as the first lymph node that receives afferent lymphatic drainage from a primary … DTPA serves as a chelating agent for technetium Tc 99m to bind [FDA Label].
Cimetropium
go.drugbank.com/drugs/DB09271InvestigationalCimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. … It is also endowed of a direct myolitic action which partially accounts for its antispasmodic activity. It has never been approved for use in the U.S. or Canada.
Bismuth subcitrate potassium
go.drugbank.com/drugs/DB09275ApprovedInvestigationalA bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Mixtures: KATACOLD 120 MG + 3.75 MG+ l MG /5 ML PEDIYATRIK ŞURUP, 100 MLProducts: NOTUSS 50 MG SR TABLET,10 TABLET, NOTUSS 50 MG SR TABLET, 20 ADETCholine C 11
go.drugbank.com/drugs/DB09277ApprovedCholine C 11 is a marker for cellular proliferation as its main molecule is a precursor for the biosynthesis of phospholipids which are essential components of all cell membranes.
Synonyms: Choline C 11Polyethylene glycol
go.drugbank.com/drugs/DB09287ApprovedInvestigationalVet approvedPEGs have a long history of gastroenterology: PEG 3350 is a common over-the-counter osmotic laxative used to relieve occasional constipation. … Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.
Mixtures: Gavilyte-N, DAXTELY FCategories: P-glycoprotein inhibitors, Compounds used in a research, industrial, or household settingOmbitasvir
go.drugbank.com/drugs/DB09296ApprovedInvestigationalOmbitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … Ombutasvir is also available as a fixed-dose combination product with [DB09297] and [DB00503] as the FDA- and Health Canada-approved product Technivie.
Categories: P-glycoprotein substrates, Treatments for Hepatitis CSynonyms: dimethyl ([(2S,5S)-1-(4-tert-butylphenyl)pyrrolidine-2,5-diyl]bis{(4,1-phenylene)carbamoyl(2S)pyrrolidine-2,1-diyl[(2S)-3-methyl-1-oxobutane-1,2-diyl]})biscarbamateParitaprevir
go.drugbank.com/drugs/DB09297ApprovedInvestigationalParitaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … Paritaprevir is also available as a fixed-dose combination product with [DB09296] and [DB00503] as the FDA- and Health Canada-approved product Technivie.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo-2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo, [1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamideAptazapine
go.drugbank.com/drugs/DB09305ExperimentalAptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity. … It antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5-HT2 receptors, agonised H1 receptors, and did not affect reuptake of serotonin or norepinephrine
Categories: Heterocyclic Compounds, 2-Ring