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Displaying results 821 - 830 of 1342 in total
  1. Drug

    Andexanet alfa

    go.drugbank.com/drugs/DB14562
    Approved

    Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and...

  2. Target

    Afadin

    go.drugbank.com/bio_entities/BE0004342
    TargetHumans

    Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs) (By similarity). Nectin- and actin...

    Synonyms: ALL1-fused gene from chromosome 6 protein
  3. Drug

    Fasidotril

    go.drugbank.com/drugs/DB20511
    Experimental

    The usage of the INN stem '-tril/trilat' in the name indicates that Fasidotril is a endopeptidase inhibitor. Fasidotril has a monoisotopic molecular weight of 443.14 Da.

  4. Drug

    Clociguanil

    go.drugbank.com/drugs/DB19775
    Experimental

    The usage of the INN stem '-nil' in the name indicates that Clociguanil is a benzodiazepine receptor antagonist/agonist. Clociguanil has a monoisotopic molecular weight of 315.07 Da.

  5. Drug

    Safironil

    go.drugbank.com/drugs/DB20553
    Experimental

    The usage of the INN stem '-nil' in the name indicates that Safironil is a benzodiazepine receptor antagonist/agonist. Safironil has a monoisotopic molecular weight of 309.17 Da.

  6. Drug

    Sotorasib

    go.drugbank.com/drugs/DB15569
    ApprovedInvestigational

    [L34288] This mutation makes up >50% of all KRAS mutations.[A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s.

  7. Drug

    Amobarbital

    go.drugbank.com/drugs/DB01351
    ApprovedIllicit

    A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmac...

  8. Drug

    Lufironil

    go.drugbank.com/drugs/DB20345
    Experimental

    The usage of the INN stem '-nil' in the name indicates that Lufironil is a benzodiazepine receptor antagonist/agonist. Lufironil has a monoisotopic molecular weight of 281.14 Da.

  9. Drug

    Bretazenil

    go.drugbank.com/drugs/DB21038
    Experimental

    The usage of the INN stem '-nil' in the name indicates that Bretazenil is a benzodiazepine receptor antagonist/agonist. Bretazenil has a monoisotopic molecular weight of 417.07 Da.

  10. Drug

    Terbequinil

    go.drugbank.com/drugs/DB19516
    Experimental

    The usage of the INN stem '-nil' in the name indicates that Terbequinil is a benzodiazepine receptor antagonist/agonist. Terbequinil has a monoisotopic molecular weight of 274.13 Da.