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Displaying results 821 - 830 of 10000 in total
  1. Drug

    N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE

    go.drugbank.com/drugs/DB07334
    Experimental

    Synonyms: N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE
  2. Drug

    N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide

    go.drugbank.com/drugs/DB07833
    Experimental

    Synonyms: N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide
  3. Drug

    Ribavirin monophosphate

    go.drugbank.com/drugs/DB14663
    Experimental

    Synonyms: Virazole 5'-phosphate, Ribavirin 5'-monophosphate
  4. Drug

    Sparfloxacin

    go.drugbank.com/drugs/DB01208
    ApprovedWithdrawn

    Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase.

    Categories: Heterocyclic Compounds, 2-Ring, 4-QuinolonesSynonyms: cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
  5. Drug

    Eluxadoline

    go.drugbank.com/drugs/DB09272
    ApprovedInvestigational

    Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). … The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system.

    Categories: Heterocyclic Compounds, 1-Ring, mu-Opioid Receptor AgonistSynonyms: 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acid
  6. Drug

    Lazertinib

    go.drugbank.com/drugs/DB16216
    ApprovedInvestigational

    [A264289] It was approved by the FDA on August 19, 2024.[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184] … [A264299, A264304] Lazertinib was first approved in South Korea on January 18, 2021, for the treatment of _EGFR_ T790M mutation-positive non-small cell lung cancer (NSCLC) with EGFR mutations.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesSynonyms: 2-PROPENAMIDE, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)-2-PYRIMIDINYL)AMINO)-4-METHOXY-2-(4-MORPHOLINYL)PHENYL)-, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE
  7. Drug

    (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3-thiazol-4-one

    go.drugbank.com/drugs/DB08710
    Experimental

    Synonyms: (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3-thiazol-4-one
  8. Drug

    Thymidine monophosphate

    go.drugbank.com/drugs/DB01643
    Investigational

    5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-deoxy-5-methyluridine 5'-(dihydrogen phosphate), 5'-TMP
  9. Drug

    Uridine monophosphate

    go.drugbank.com/drugs/DB03685
    Investigational

    5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5'-uridylic acid, Uridine 5'-monophosphate
  10. Drug

    Flurocitabine

    go.drugbank.com/drugs/DB20317
    Experimental

    Flurocitabine is a small molecule drug. … Flurocitabine has a monoisotopic molecular weight of 243.07 Da.

    Synonyms: 5-fluorocyclocytidine, 5'-fluorocyclocytidine